Avancerad sökning

Visar resultat 6 - 10 av 17 avhandlingar som matchar ovanstående sökkriterier.

1. 6. Metal Oxide Nanoparticles for Contrast Enhancement in Magnetic Resonance Imaging : Synthesis, Functionalization and Characterization

   Författare :Maria Ahrén; Kajsa Uvdal; Jan Kehr; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : This thesis work focuses on the design and production of nanoparticle based contrast agents for signal enhancement in magnetic resonance imaging (MRI). Three different synthesis routes are explored, primarily to produce crystalline gadolinium oxide (Gd2O3) nanoparticles, and surface modification is done to obtain stable, dispersible, biocompatible probes inducing high proton relaxivities. LÄS MER

3. 7. Modélisation théorique de la spectroscopie d'actinides des solvatés

   Författare :Cecile Danilo; Ulf Wahlgren; Valerie Vallet; Jean-Pierre Flament; Timo Fleig; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Actinides; spectra; solution; Chemical physics; Kemisk fysik; kemisk fysik; Chemical Physics;

   Sammanfattning : The framework of this PhD is the interpretation of Nuclear Magnetic Relaxation Dispersion experiments performed on solvated U4+, NpO2+ and PuO22+, which all have an f2 configuration. Unexpectedly the two actinyl ions have a much higher relaxivity than U4+. LÄS MER

4. 8. Synthesis, Surface Modification, and Characterization of Metal Oxide Nanoparticles : Nanoprobes for Signal Enhancement in Biomedical Imaging

   Författare :Linnéa Selegård; Kajsa Uvdal; Pentti Tengvall; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : In this thesis we investigate crystalline metal oxide nanoparticles of our own design to obtain nanoprobes for signal enhancement and bioimaging purposes. We report fabrication, surface modification and characterization of nanoparticles based on zinc (Zn), and rare earths (i.e. gadolinium (Gd) and europium (Eu)) singly and in combination. LÄS MER

5. 9. Synthesis of Polymeric Nanocomposites for Drug Delivery and Bioimaging

   Författare :Heba Asem; Joydeep Dutta; Moustapha Hassan; Fei Ye; Jöns Hilborn; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biodegradable polymers; SPION; QDs; drug delivery; cytotoxicity; MRI; in vivo fluorescence imaging; biodistribution; Fysik; Physics;

   Sammanfattning : Nanomaterials have gained great attention for biomedical applications due to their extraordinary physico-chemical and biological properties. The current dissertation presents the design and development of multifunctional nanoparticles for molecular imaging and controlled drug delivery applications which include biodegradable polymeric nanoparticles, superparamagnetic iron oxide nanoparticles (SPION)/polymeric nanocomposite for magnetic resonance imaging (MRI) and drug delivery, manganese-doped zinc sulfide (Mn:ZnS) quantum dots (QDs)/ SPION/ polymeric nanocomposites for fluorescence imaging, MRI and drug delivery. LÄS MER

7. 10. MRI Perfusion Measurements using Magnetic Susceptibility Effects: : Calibration Approaches and Contrast Agent Quantification

   Författare :Emelie Lind; Lund Medicinsk strålningsfysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; contrast agent; cerebral blood flow; cerebral blood volume; mean transit time; perfusion; dynamic susceptibility contrast MRI; magnetic susceptibility;

   Sammanfattning : Exchange of oxygen and nutrients between blood and tissue occurs at the capillary level of the blood system. The blood volume flow rate in the capillaries is often referred to as perfusion, and knowledge about perfusion provides important information about the function and viability of the tissue, for example, in patients with ischaemic stroke, cancer, and neurodegenerative diseases. LÄS MER