Sökning: "SPION"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet SPION.

  1. 1. Synthesis of Polymeric Nanocomposites for Drug Delivery and Bioimaging

    Författare :Heba Asem; Joydeep Dutta; Moustapha Hassan; Fei Ye; Jöns Hilborn; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biodegradable polymers; SPION; QDs; drug delivery; cytotoxicity; MRI; in vivo fluorescence imaging; biodistribution; Fysik; Physics;

    Sammanfattning : Nanomaterials have gained great attention for biomedical applications due to their extraordinary physico-chemical and biological properties. The current dissertation presents the design and development of multifunctional nanoparticles for molecular imaging and controlled drug delivery applications which include biodegradable polymeric nanoparticles, superparamagnetic iron oxide nanoparticles (SPION)/polymeric nanocomposite for magnetic resonance imaging (MRI) and drug delivery, manganese-doped zinc sulfide (Mn:ZnS) quantum dots (QDs)/ SPION/ polymeric nanocomposites for fluorescence imaging, MRI and drug delivery. LÄS MER

  3. 2. Nanoparticles for multifunctional drug delivery systems

    Författare :Jian Qin; Mamoun Muhammed; Paavo K J Kinnunen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; drug delivery; stimuli-sensitive; SPION; PLLA; PNIPAAm; gold; MRI; cytotoxicity; Pluronic; phase transfer; Materials chemistry; Materialkemi;

    Sammanfattning : Multifunctional drug delivery systems incorporated with stimuli-sensitive drug release, magnetic nanoparticles and magnetic resonance (MR) T2 contrast agents is attracting increasing attention recently. In this thesis, works on polymer nanospheres response to temperature change, superparamagnetic iron oxide nanoparticles (SPION)/polymeric composite materials for MR imaging contrast agents are summarized. LÄS MER

  4. 3. Design of Functional Polymeric Nanoparticles for Biomedical Applications

    Författare :Heba Asem; Eva Malmström; Tim Bowden; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biodegradable polymers; SPION; PISA; RAFT; nanoparticles; drug delivery; cytotoxicity; MRI; in vivo fluorescence imaging; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Most of the devastating diseases such as cancer are relatively incurable and have high risks of relapse. Therefore, persistent endeavors have been devoted to improve patient survival rate and quality of life. LÄS MER

  5. 4. Nano-Engineered Contrast Agents : Toward Multimodal Imaging and Acoustophoresis

    Författare :Satya V.V.N. Kothapalli; Dmitry Grishenkov; Lars-Åke Brodin; Andreas Michael Versluis; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Nano-engineered microbubbles; SPION nanoparticles; Acoustic characterization of MBs; Fracturing mechanism of MBs; Opto-acoustics; Acoustophoresis; Physics; Fysik; Järnvägsgruppen - Ljud och vibrationer; Järnvägsgruppen - Ljud och vibrationer; Teknik och hälsa; Technology and Health;

    Sammanfattning : Diagnostic ultrasound (US) is safer, quicker and cheaper than other diagnostic imaging modalities. Over the past two decades, the applications of US imaging has been widened due to the development of injectable, compressible and encapsulated microbubbles (MBs) that provide an opportunity to improve conventional echocardiographic imaging, blood flow assessment and molecular imaging. LÄS MER

  7. 5. Ultrasound Contrast Agents Loaded with Magnetic Nanoparticles : Acoustic and Mechanical Characterization

    Författare :VeeraVenkata Satyanarayana Kothapalli; Lars-Åke Brodin; Jan Engvall; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Ultrasound contrast agents; SPION nanoparticles; harmonic oscillation; backscattering power; attenuation coefficient; phase velocity; nonlinear equation of motion;

    Sammanfattning : The current methodologies in body scanning diagnostic uses different simultaneous imaging modalities like Ultrasound (US), magnetic resonance imaging (MRI), single photon emission tomography (SPECT) and positron emission tomography (PET). The field requires combination of different modalities for effective use in clinical diagnostics. LÄS MER