Sökning: "regeneration niche"

Visar resultat 11 - 15 av 17 avhandlingar innehållade orden regeneration niche.

  1. 11. The Role of Hepatic Leukemia Factor in Hematopoiesis

    Författare :Karolina Komorowska; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; Hematopoietic Stem Cells; knockout mice; HLF; Transcription Factor; aging;

    Sammanfattning : The development of therapeutic methods based on stem cells (e.g. cell therapy, activating regeneration and organ transplantation), known as regenerative medicine, is still a novel area in the field of life sciences. LÄS MER

  3. 12. The effect of astrocytes and reactive gliosis on neurogenesis and astrogenesis in mice

    Författare :Åsa Widestrand; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astrocytes; intermediate filaments; neural stem cells; neurogenesis; astrogenesis; hippocampus;

    Sammanfattning : Astrocytes are the most common cell type in mammalian central nervous system (CNS). Glial fibrillary acidic protein (GFAP) and vimentin constitute intermediate filaments (known also as nanofilaments), a part of the cytoskeleton, in astrocytes. LÄS MER

  4. 13. Tissue remodelling in pulmonary fibrosis linked to 5-HT2 receptor activation

    Författare :Anna Löfdahl; Lungbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Serotonin 5HT ; Serotonin class 2 receptor antagonist; Fibroblast; Pulmonary fibrosis; Extracellular matrix ECM ;

    Sammanfattning : After an injury, an immediate reparative response is triggered to replace the damaged tissue, however, in fibrosis, cells remain active despite wound resolution causing a steady build-up of fibrotic tissue. In pulmonary fibrosis,there is a constant regeneration and remodelling of lung tissue where the thin architecture of alveoli become thickened, hampering efficient diffusion of oxygen, as seen in diseases like idiopathic pulmonary fibrosis (IPF). LÄS MER

  5. 14. Dental mesenchymal stem cells

    Författare :Nina Kaukua; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mesenchymal stem cells have been found in various tissues and act as source for renewal and repair. The mouse incisor tooth continuously grows throughout life, implicating that there are stem cell niches constantly contributing with cells. The composition of these stem cell niches is not fully understood. LÄS MER

  7. 15. Cartilage Tissue Engineering; the search for chondrogenic progenitor cells and associated signalling pathways

    Författare :Maria Thornemo; Göteborgs universitet; []
    Nyckelord :stem cell; progenitor cell; tissue engineering; cartilage; articular chondrocytes;

    Sammanfattning : The socioeconomic cost of articular cartilage related diseases in the Western world is very high. The suffering of the individual patient is even more problematic. LÄS MER