Sökning: "protein quantitation"

Visar resultat 6 - 10 av 20 avhandlingar innehållade orden protein quantitation.

1. 6. Characterization of Molecular Adsorption Using Liquid Chromatography and Mass Spectrometry

   Författare :Torgny Undin; Andreas Dahlin; Sara Bergström Lind; Jonas Bergquist; Elsa Lundanes; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

   Sammanfattning : Molecular adsorption is a key feature in several disciplines of chemistry, covering as diverse fields as chromatographic separation to biomaterial development. This thesis aims at developing methods and techniques for the characterization of molecular adsorption at the liquid-solid interface. LÄS MER

3. 7. Chemical labelling methods for gel free based proteomics

   Författare :Åsa Wåhlander; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biotechnology; Bioteknik; Biokemisk teknik; Biochemical technology; 2D-HPLC; isotopes; labelling; proteomics; mass spectrometry;

   Sammanfattning : In this thesis different aspects of gel free procedures for mass spectrometry based proteome analysis are addressed, with emphasis on labelling techniques. It is based on three original articles where the effects imposed onto peptides upon modification are investigated, and the development of a new type of labelling strategy is described. LÄS MER

4. 8. Development of Liquid-based Separation Techniques using Tailored Surfaces for Analysis of Biological Samples

   Författare :Emilia Hardenborg; Jonas Bergquist; Marit Andersson; Alejandro Cifuentes; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aqueous humor; biological samples; capillary electrophoresis; coatings; drugs; liquid chromatography; molecular imprinted polymers; peptides; proteins; pseudoexfoliation; Analytical chemistry; Analytisk kemi;

   Sammanfattning : Development and improvement of analytical techniques are vital in analytical chemistry research. This thesis describes the development and use of tailored surfaces for bioanalytical applications. LÄS MER

5. 9. Piperaquine and Metabolites - Bioanalysis and Pharmacokinetics

   Författare :Mohd Yusmaidie Aziz; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bioanalysis; Pharmacokinetics; Piperaquine; Malaria;

   Sammanfattning : Antimalarial piperaquine (PQ) is currently used as a partner drug with dihydroartemisinin (DHA), exhibiting high cure rates (>95%) for P. falciparum. Despite its raising usage worldwide with DHA, PQ is synthetically developed outside of big pharma pipelines. LÄS MER

7. 10. Type 2 Cystatins. Studies on the role of the major cystatin, cystatin C, in mice and on properties and distribution of the novel human cystatins F, G, H and I

   Författare :Carl-Michael Nathanson; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical chemistry; Klinisk kemi; enzyme kinetics; eosinophilic granulocytes; expression pattern; pleural effusion; knockout mouse; Cysteine peptidase; cystatin;

   Sammanfattning : The aim the thesis work was to study the human cystatins C, E/M, F, G, H and I both in vivo and in vitro. A mouse devoid of cystatin C was used for the cystatin C studies. The levels of cystatins C, E/M and F were measured in pleural effusion samples of patients with various lung disorders. LÄS MER