Sökning: "probe design strategy"

Visar resultat 6 - 10 av 13 avhandlingar innehållade orden probe design strategy.

  1. 6. Proximity Ligation Assays for Disease Biomarkers Analysis

    Författare :Rachel Yuan Nong; Ulf Landegren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proximity ligation assay; blood biomarkers; protein interactions; pathway analysis; single molecule; next-generation sequencing; Molekylär medicin; Molecular Medicine;

    Sammanfattning : One of the pressing needs in the field of disease biomarker discovery is new technologies that could allow high performance protein analysis in different types of clinical material, such as blood and solid tissues. This thesis includes four approaches that address important limitations of current technologies, thus enabling highly sensitive, specific and parallel protein measurements. LÄS MER

  3. 7. RNA-based spatial characterization of cell and tissue heterogeneity

    Författare :Elin Lundin; Mats Nilsson; Rickard Sandberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Padlock probes; in situ sequencing; single cell resolution; single nucleotide variant resolution; spatial transcription profiling; Biochemistry; biokemi;

    Sammanfattning : Technical advances in cell biology have revolutionized the field of cell biology. With new technology it is now possible to address scientific questions in cell biology at the molecular level. LÄS MER

  4. 8. Measurements of hard X-ray polarization from the Crab and Cygnus X-1

    Författare :Victor Mikhalev; Mark Pearce; Herman Marshall; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fysik; Physics; Fysik; Physics;

    Sammanfattning : Polarimetry provides insights into the emission mechanisms of astrophysical sources by elucidating their magnetic field and geometry. Hard X-rays are produced in \mbox{regions} with strong magnetic fields or strong gravitational effects, which makes them a probe of extreme environments. LÄS MER

  5. 9. Synthesis, Surface Modification, and Characterization of Metal Oxide Nanoparticles : Nanoprobes for Signal Enhancement in Biomedical Imaging

    Författare :Linnéa Selegård; Kajsa Uvdal; Pentti Tengvall; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : In this thesis we investigate crystalline metal oxide nanoparticles of our own design to obtain nanoprobes for signal enhancement and bioimaging purposes. We report fabrication, surface modification and characterization of nanoparticles based on zinc (Zn), and rare earths (i.e. gadolinium (Gd) and europium (Eu)) singly and in combination. LÄS MER

  7. 10. Improved PWB test methodologies

    Författare :Abdelghani Renbi; Erik Larsson; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Industriell elektronik; Industrial Electronics;

    Sammanfattning : Printed Wiring Board (PWB) and Printed Circuit Board Assembly (PCBA) testing aims to ensure an error free board after the etching and the assembly processes. After the etching process, several types of errors might occur such as opens and bridges, which are already, showstoppers in Direct Current (DC) applications. LÄS MER