Sökning: "spatial transcription profiling"

Hittade 4 avhandlingar innehållade orden spatial transcription profiling.

  1. 1. RNA-based spatial characterization of cell and tissue heterogeneity

    Författare :Elin Lundin; Mats Nilsson; Rickard Sandberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Padlock probes; in situ sequencing; single cell resolution; single nucleotide variant resolution; spatial transcription profiling; Biochemistry; biokemi;

    Sammanfattning : Technical advances in cell biology have revolutionized the field of cell biology. With new technology it is now possible to address scientific questions in cell biology at the molecular level. LÄS MER

  3. 2. Spatial and temporal regulation of neural stem cells in the developing brain by PRDM16

    Författare :Li He; Qi Dai; Christos Samakovlis; Simon Hippenmeyer; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain development; Neural stem cell; PRDM16; BMP signaling; Choroid plexus; Cortical neurogenesis; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The mammalian brain comprises a large number and diversity of neurons and non-neural cells. Most of these cell types derive from a single sheet of neuroepithelium (NE) that contains a limited pool of neural stem cells (NSCs).  NSCs in the developing brain are under complex regulation to achieve maximum daughter cell type diversity. LÄS MER

  4. 3. A study on the TFIID subunit TAF4

    Författare :Adrian Brunkhorst; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Transcription is a fundamental process in the regulation of gene expression. It has long been generally believed that certain so called basal factors of the transcriptional machinery are ubiquitously expressed. LÄS MER

  5. 4. Functional analysis of Ipf1/Pdx1, MFng and Id during pancreatic growth and differentiation

    Författare :Per Svensson; Helena Edlund; Henrik Semb; Umeå universitet; []
    Nyckelord :pancreas; proliferation; differentiation; signalling; expression; FgfR2IIIb; ErbB3; spondin1; MFng; Id; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

    Sammanfattning : The pancreas is an endodermally derived organ consisting of three major cell lineages. The endocrine cells, organised into the Islets of Langerhans, regulate blood glucose homeostasis by producing and secreting hormones such as glucagon and insulin into the bloodstream. LÄS MER