Avancerad sökning

Visar resultat 1 - 5 av 13 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Probing for innovation : how small design teams collaborate

   Författare :Mattias Bergström; Tim McAloone; Luleå tekniska universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Funktionella produkter; Functional Product Development;

   Sammanfattning : Ongoing globalization is placing greater demands on industry. One strategy to stay competitive is to move from supplying only hardware to supplying total offers, e.g. thrust on wings or power by the hour. LÄS MER

3. 2. Detection and Quantification of Variable Viral RNA by Real-Time PCR Assays

   Författare :Shaman Muradrasoli; Jonas Blomberg; Göran Friman; Maria Brytting; Uppsala universitet; []
   Nyckelord :Virology; Diagnosis of Viral RNA; QPCR; RNA virus; broadly targeted PCR; probe design strategy; Infectious diseases; Medicin; Medicine;

   Sammanfattning : As the area of nucleic acid based technologies develops, so will our understanding of how structural variations in DNA and RNA pathogens are associated with disease. The overall goal of this thesis is the development of broadly targeted measurement techniques for variable viral RNA by Real-Time PCR (here referred to as quantitative reverse transcriptase PCR, QRT-PCR). LÄS MER

4. 3. Padlock Probe-Based Nucleic Acid Amplification Tests : Point-of-care Diagnostics of Infectious Diseases

   Författare :Sibel Ciftci; Mats Nilsson; Jonas Klingström; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nucleic Acid Amplification; Isothermal Amplification Methods; Padlock Probes; Rolling Circle Amplification; Molecular Diagnostics; Infectious Disease Diagnostics; Virus; Point-of-Care; Biochemistry; biokemi;

   Sammanfattning : Recent advancements in molecular biology and biotechnology have pushed the field of molecular diagnostics much further to benefit the society towards smart access for rapid and simplified health care. In this context, point-of-care (PoC) technologies that bring the inventions in diagnostics closer to bedside settings draw attention. LÄS MER

5. 4. Synthesis and Applications of Dynamic Multivalent Nanostructures

   Författare :Kitjanit Neranon; Olof Ramström; Aldrik Velders; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; multivalent nanostructures; self-assembly; metal-ligand exchange; dynamic covalent chemistry; bipyridine derivatives; dendrimers; liposomes; drug delivery; antimicrobial materials; fluorescent probe; plasmonic chemistry; gold surface functionalization; Kemi; Chemistry;

   Sammanfattning : This thesis focuses on the design, synthesis and development of dynamic multivalent nanostructures such as supramolecular dendrimers, liposomes and gold-functionalized nanostructures. These structures can be used for drug delivery and molecular sensing applications. LÄS MER

7. 5. Technology development for genome and polymorphism analysis

   Författare :Magnus Jobs; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :SNP; Genotyping technology; DASH; Array technology; Assay design;

   Sammanfattning : Single nucleotide polymorphism (SNP) is widely expected to provide a multitude of benefits in areas of medical research. There is, however, a growing disparity between the rate of SNP discovery and the development of effective technologies for large scale SNP scoring. LÄS MER