Sökning: "posttranscriptional"

Visar resultat 6 - 10 av 31 avhandlingar innehållade ordet posttranscriptional.

  1. 6. Posttranscriptional regulation of gene expression by cis-acting regulatory elements in HPV type 16

    Författare :Xiaomin Zhao; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  3. 7. TNFalpha expression in monocytes/macrophages

    Författare :Karolina Andersson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; Protein kinase; Macrophage; TNF;

    Sammanfattning : The recognition of microbes or microbial products by leukocytes is a key event in innate immunity. Binding of microbial products to cell surface receptors on phagocytes induce a response that includes the production of inflammatory mediators. One such mediator is the cytokine tumour necrosis factor alpha (TNF). LÄS MER

  4. 8. Nuclear Organization of Gene Expression in Adenovirus Infected Cells

    Författare :Anders Aspegren; Lars Wieslander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Adenovirus; mRNA; transport; IGCs; E434kDa; E1B55kDa; NES; snRNP; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Sammanfattning : Adenovirus infected cells provide a good model system for studying nuclear organization during RNA production and transport. This thesis is focused on the dynamic organization of splicing factors during the late phase of Adenovirus infection in HeLa cells, the nuclear localization of viral RNA, and the pathway used for viral RNA transport to the cytoplasm. LÄS MER

  5. 9. The functional organization of nuclear envelope proteins

    Författare :Santhosh Kumar Gudise; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In eukaryotic cells, the nucleus is enclosed by a double lipid membrane, termed the nuclear envelope (NE). The NE consists of the outer nuclear membrane (ONM), the inner nuclear membrane (INM), the nuclear pore complexes (NPCs) and the nuclear lamina. LÄS MER

  7. 10. Microarray Analysis of mRNA Decay Assays and Prediction of Drug Target Conservation

    Författare :Alexandra Jauhiainen; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microarray analysis; mRNA decay; evolutionary conservation; ecotoxicology; environmental risk assessments; ecotoxicology;

    Sammanfattning : This thesis contains two papers concerning (I) the evolutionary conservation of drug targets and its potential use in environmental risk assessments and (II) mRNA degradation as a control mechanism during osmotic stress in the yeast S. cerevisiae. Environmental risk assessments are needed for the approval of new pharmaceutical compounds. LÄS MER