Sökning: "postmenopausal breast cancer"

Visar resultat 31 - 35 av 48 avhandlingar innehållade orden postmenopausal breast cancer.

  1. 31. Thyroid hormones and breast cancer-prospective studies on incidence, mortality and prognostic factors

    Författare :Ada Tosovic; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Thyroid hormones and breast cancer-prospective studies on incidence, mortality and prognostic factors The aim of this thesis was to investigate in a prospective design, thyroid hormones in relation to breast cancer risk, mortality and prognostic factors. The association between total triiodothyronine (T3) levels and breast cancer risk was studied in 2185 women with146 incident breast cancer cases. LÄS MER

  3. 32. p53 Alterations in Breast Cancer Related to Prognosis and Results of Therapy

    Författare :Askmalm Marie Stenmark-Askmalm; Dick Killander; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Breast cancer is the most common malignant tumour disease and also the main cause of cancer-related deaths among women. The lifetime risk in western countries is 10%. The basic treatment for a patient with a localised tumour is surgery. LÄS MER

  4. 33. Sex steroid effects on normal breast tissue

    Författare :Gunnar Söderqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Estrogen receptor; progesterone receptor; proliferation; breast epithelialcells; mammary epithelium; sulfatase; 17 HSD; regional differences; sex steroids;

    Sammanfattning : In Sweden, it is estimated that about one million women are treated with estrogen/progestogen for contraception and hormone replacement therapy (HRT). The possibility of an increased cancer risk in target organs has been vividly discussed for many years. LÄS MER

  5. 34. Risk factors for ipsilateral breast tumor recurrence and uncontrolled local disease

    Författare :Kristina Dalberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast cancer; ipsilateral breast tumor recurrence; uncontrolled local disease; risk factors;

    Sammanfattning : The aims of the study were to assess intrinsic and treatment related risk factors for ipsilateral breast tumor recurrence (IBTR) and uncontrolled local disease (ULD) following breast-conserving surgery of early-stage invasive breast cancer. In a cohort of 759 women with T1-T2 tumors risk factors were evaluated. LÄS MER

  7. 35. Extrahepatic cytochrome P450s : relation to cancer susceptibility

    Författare :Tove Rylander Rudqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cytochrome P450 (CYP) enzymes in extrahepatic tissues may play important roles in regulating the capacity of individual cells to metabolize environmental carcinogens and hormones. In this thesis, we characterized the cytochrome P450 profile of the human normal breast and investigated whether polymorphisms in the genes encoding the estrogen metabolizing enzymes CYP1131 and Catechol-O-methyltransferase (COMT) were associated with breast or endometrial cancer risk. LÄS MER