Sökning: "overtreatment."

Visar resultat 1 - 5 av 27 avhandlingar innehållade ordet overtreatment..

  1. 1. Surveillance and follow-up of early prostate cancer

    Författare :Mats Steinholtz Ahlberg; Anna Bill-Axelson; Lars Holmberg; Anna Lantz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; active surveillance; follow-up; biochemical recurrence; triggers for transition to radical treatment; overdiagnosis; overtreatment.; Urologi; Urology;

    Sammanfattning : Active surveillance (AS) for prostate cancer was introduced to address overtreatment resulting from prostate-specific antigen (PSA) testing. Despite advancements such as Magnetic Resonance Imaging (MRI) and targeted biopsies, PSA remains crucial in prostate cancer diagnostics, leading to ongoing challenges of overdiagnosis and overtreatment. LÄS MER

  3. 2. Potential overtreatment during life-limiting illness and end of life in older adults

    Författare :Máté Szilcz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background. A growing body of evidence suggests that older patients are subject to potential overtreatment at the end of life, characterised by disease modifying therapies, preventive medications, and frequent care transitions. LÄS MER

  4. 3. Living and dying with prostate cancer : Population-based register studies

    Författare :Magdalena Lycken; Anna Bill-Axelson; Lars Holmberg; Jan-Erik Damber; Uppsala universitet; []
    Nyckelord :Androgen deprivation therapy; Palliative medicine; Population-based study; Prostate cancer.; Urologi; Urology;

    Sammanfattning : Tailored treatment with adequate timing is essential for the quality of prostate cancer care at all stages. Overtreatment should be avoided due to the side effects, but undertreatment may on the other hand lead to progression and death. LÄS MER

  5. 4. Personalized prostate cancer management : AI-assisted prostate pathology and improved active surveillance

    Författare :Henrik Olsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostate cancer is a major global health concern and is the most common cancer-related cause of death in Sweden. Prostate cancer screening using PSA has been shown to reduce prostate cancer mortality but also leads to significant overdiagnosis and overtreatment of low-risk cancers. LÄS MER

  7. 5. Cyclin A and cyclin E as prognostic factors in early breast cancer

    Författare :Cecilia Ahlin; Marie-Louise Fjällskog; Carl Blomqvist; Göran Landberg; Uppsala universitet; []
    Nyckelord :Oncology; breast cancer; chemotherapy; cyclin A; cyclin E; aberrant cyclin E; Ki-67; TMA; Onkologi;

    Sammanfattning : Breast cancer is one of the most common malignancies in women. Due to early detection and the use of screening programs approximately 60% of all new cases lack lymph node involvement. Today, a substantial proportion of these women will be offered adjuvant systemic chemotherapy. LÄS MER