Sökning: "ovarian"

Visar resultat 16 - 20 av 323 avhandlingar innehållade ordet ovarian.

  1. 16. Effect of ovarian surgery on ovarian reserve and fertility

    Författare :Tekla Lind; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The objective of this thesis was to investigate short- and long-term effects of ovarian surgery on the ovarian reserve of women of reproductive age. This research also considered their reproductive outcomes with regard to conceiving spontaneously or using assisted reproductive techniques (ART). LÄS MER

  3. 17. Mechanisms for immune escape in epithelial ovarian cancer

    Författare :Pernilla Israelsson; Ulrika Ottander; Lucia Mincheva-Nilsson; Eva Lundin; Ivan Nagaev; Karin Sundfeldt; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; ovarian cancer; high-grade serous cancer; EOC; HGSC; HGSOC; tumor microenvironment; immune escape; immune suppression; cytokines; exosomes; NKG2D; MICA B; ULBP1-3; DNAM-1; surgery; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Tumors develop mechanisms to subvert the immune system, constituting immune escape. Epithelial ovarian cancer (EOC), the deadliest of all gynecological malignancies, uses a variety of mechanisms to undermine immune surveillance, aiding its establishment and metastatic spreading. LÄS MER

  4. 18. Human ovarian surface epithelium and ovarian cancer. Aspects of growth regulation

    Författare :Karin Ivarsson; Göteborgs universitet; []
    Nyckelord :ovarian cancer ovarian surface epithelium interleukin-8 C EBP gonadotropins steroids;

    Sammanfattning : The ovary is covered with a single layer of epithelial cells, the ovarian surface epithelium (OSE). The OSE is degraded during every menstrual cycle to enable ovulation, and is subsequently reconstituted to cover the rupture site. This single cell layer is proposed as the origin for about 90 % of all ovarian cancers. LÄS MER

  5. 19. Intrinsic subtypes and prognostic implications in epithelial ovarian cancer

    Författare :Jenny-Maria Jönsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; gene expression profiling; Lynch syndrome; targeted deep sequencing; chromatin remodeling; molecular subtypes; endocrine receptors; prognostic factors; tumor heterogeneity;

    Sammanfattning : Ovarian cancer is the seventh most common cancer in women globally, with approximately 240,000 new cases annually. Although a rare disease, it is the most lethal gynecologic malignancy. Unspecific symptoms result in late diagnosis and a generally poor prognosis. LÄS MER

  7. 20. New Prognostic Markers in Stage III Serous Ovarian Adenocarcinomas

    Författare :Karolina Partheen; Göteborgs universitet; []
    Nyckelord :Ovarian cancer; Biomarker; Prognostic factors; Integrin beta 3;

    Sammanfattning : Ovarian carcinoma is the fifth most common cause of cancer death in Swedish women. Patients with advanced-stage disease respond differently to treatment, and the clinical outcome is difficult to predict for an individual patient. LÄS MER