Sökning: "Miles Trupp"
Hittade 3 avhandlingar innehållade orden Miles Trupp.
1. Neurotrophic signalling by GDNF and its receptors
Sammanfattning : Many investigators have sought a polypeptide which would alleviate the neuronal loss associated with Parkinson's disease--specifically dopaminergic neurons of the ventral mesencephalon. The survival of this population of neurons has been known for some time to be promoted by soluble factors present in the conditioned media of glial cell lines. LÄS MER
2. Imaging neurochemical changes associated with Parkinson´s disease and L-DOPA-induced dyskinesia using mass spectrometry
Sammanfattning : Parkinson’s disease (PD), caused by a loss of midbrain dopamine neurons, is the second most common neurodegenerative disease worldwide after Alzheimer’s disease. The primary treatment choice for PD is L-DOPA, the precursor for dopamine, which only affects symptoms and does not inhibit disease progression. LÄS MER
3. The release of histone proteins from cells via extracellular vesicles
Sammanfattning : Histones are chromatin-associated proteins localized to the nucleus. However, extracellular histones are present in biofluids from healthy individuals and become elevated under disease conditions, such as neurodegeneration and cancer. LÄS MER