Sökning: "Aleksandra Bulka"

Hittade 1 avhandling innehållade orden Aleksandra Bulka.

1. 1. Genetic differences in neuropathy and opioid responses in rats

   Författare :Aleksandra Bulka; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Allodynia; genetic difference; neuropathic pain; NMDA-receptor; opioids; rat strains; pharmacokinetics; tolerance.;

   Sammanfattning : The studies examined mechanisms and treatments of experimental neuropathic pain with particular emphasis on the differences between rat strains and sub-strains in basal nociceptive sensitivity, development of neuropathic behaviors and sensitivity to opioid analgesia. In order to study the mechanisms that mediate mechanical allodynia (touch-evoked pain) following ischemic nerve injury to the sciatic nerve in rats, the myelinated primary afferents have been examined in the injured and intact nerves. LÄS MER