Sökning: "neurokemi och neurotoxikologi"

Visar resultat 21 - 25 av 32 avhandlingar innehållade orden neurokemi och neurotoxikologi.

  1. 21. On cell-penetrating peptides and cell-junction interactions

    Författare :Maria Lindgren; Nicholas Bodor; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : Cell-penetrating peptides have the remarkable ability to carry hydrophilic macromolecules over the cellular membrane in an energy and protein independent manner. To synthesise and characterise new variants of cell-penetrating peptides, mainly aimed at finding analogues with minimised side effects and efficient cellular delivery, was one of the two main objectives of this thesis. LÄS MER

  3. 22. Role of IL-1RAcP and IL-1ra in IL-1 signalling : molecular biological and transgenic studies

    Författare :Johan Lundkvist; Alberto Mantovani; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Other chemistry; Övrig kemi;

    Sammanfattning : IL-1 is a proinflammatory cytokine which causes systemic responses such as fever, increased neuroendocrine activity, sympathetic outflow and increased immune responses. Activation of the transcription factor NFkB is one of the molecular mechanisms involved in IL-1 signalling. LÄS MER

  4. 23. On Fever Mechanisms & Preoptic Signalling

    Författare :Anna Sundgren Andersson; Robert Dantzer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : Fever, a 1-4 °C elevation of the body temperature, is part of the systemic inflammatory response to infection or tissue damage, and it is believed to be a potent host defence. The underlying physiological mechanisms of the febrile response are one of the two main objectives in this thesis, where studies conducted in whole animals (rats and mice), chiefly aimed at clarifying the cytokine cascade in fever. LÄS MER

  5. 24. Mechanisms of acrylamide-induced neurite degeneration and in vitro - in vivo extrapolation of toxicity

    Författare :Marika Nordin-Andersson; Frode Fonnum; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : .... LÄS MER

  7. 25. Role of the neuropeptide galanin and its receptors in signal transduction

    Författare :Khadijeh Rezaei; Anna-Lena Hulting; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : .... LÄS MER