Sökning: "multidimensional chromatography"

Visar resultat 6 - 8 av 8 avhandlingar innehållade orden multidimensional chromatography.

  1. 6. Functional Proteome analysis of the molecular mechanism of (myo)fibroblast differentiation

    Författare :Johan Malmström; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fibroblast myofibroblast extracellular matrix asthma COPD PDGF TGF-beta heparan sulfate proteoglycans proteomics mass spectrometry MALDI ESI; Metabolism; Biochemistry; Biokemi; metabolism;

    Sammanfattning : Tissue remodeling is observed in several physiological conditions such as embryogenesis, senescence, wound healing and pregnancy, as well as in several pathological conditions such as fibrosis and tumorgenesis. Fibroblasts play a key role in this tissue remodeling due to their capability of altering the turnover of the extracellular matrix. LÄS MER

  3. 7. Electrifying the Molecules of Life : Peptide and Protein Analysis by Capillary Electrophoresis Coupled to Electrospray Ionization Mass Spectrometry

    Författare :Magnus Wetterhall; Jonas Bergquist; Karin E. Markides; Dominic M. Desiderio; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Capillary electrophoresis CE ; Electrospray ionization ESI ; Mass spectrometry MS ; Peptides; Proteins; Cerebrospinal fluid CSF ; Graphite coating; Monomer coating; Polymer coating; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Sammanfattning : This thesis describes the current status and novel aspects of the analysis of the molecules of life, i.e. peptides and proteins, using capillary electrophoresis (CE) coupled to mass spectrometry (MS) via (sheathless) electrospray ionization (ESI). Early reports of sheathless CE-ESI-MS were plagued by limited lifetimes of the electrospray emitter. LÄS MER

  4. 8. Microextraction for usage in environmental monitoring and modelling of nitroaromatic compounds and haloanisoles

    Författare :Sofie Jönsson; Bert van Bavel; Tomas Öberg; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PCA; PLS; QSPR; SPME; MEPS; nitroaromatic compounds; TCA; TBA; Chemistry; Kemi; Kemi; Chemistry;

    Sammanfattning : Processes in the environment are often complex and the description and prediction of the behaviour of environmental pollutants requires sophisticated methodology including multidimensional technology. Multivariate statistical methods including principal component analysis (PCA) and partial least squares projection to latent structures (PLS) were used to characterise several nitroaromatic compounds according to a large number of chemical and physical properties. LÄS MER