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Visar resultat 1 - 5 av 229 avhandlingar som matchar ovanstående sökkriterier.

1. 1. The emotional motor system and gastrointestinal symptoms

   Författare :Pontus Karling; Lars Agréus; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anxiety; ANS; autonomic nervous system; cortisol; DST; emotional motor system; functional; gastrointestinal symptoms; GSRS-IBS; gut; HADS; heart rate variability; HPA axis; IBS; irritable bowel syndrome; stress; unipolar depression; val158met COMT polymorphism; Gastroenterology; Gastroenterologi;

   Sammanfattning : There is a significant comorbidity between anxiety/depression and functional gastrointestinal syndromes, such as irritable bowel syndrome (IBS) and functional dyspepsia. The pathophysiological link between emotions and the gut is not known. LÄS MER

3. 2. Sensor-based knowledge- and data-driven methods : A case of Parkinson’s disease motor symptoms quantification

   Författare :Somayeh Aghanavesi; Mark Dougherty; Mobyen Uddin Ahmed; Högskolan Dalarna; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Parkinson’s disease; motion sensors; motor symptoms; smartphone; microdata; multivariate analysis; data-driven; knowledge-driven; support vector machine stepwise regression; predictive models; Complex Systems – Microdata Analysis; Komplexa system - mikrodataanalys;

   Sammanfattning : The overall aim of this thesis was to develop and evaluate new knowledge- and data-driven methods for supporting treatment and providing information for better assessment of Parkinson’s disease (PD).PD is complex and progressive. There is a large amount of inter- and intravariability in motor symptoms of patients with PD (PwPD). LÄS MER

4. 3. Dopaminergic stabilizers for the treatment of schizophrenia. Rat studies focusing on negative symptoms and mechanisms of action

   Författare :Johan P. Rung; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ACR16; dopaminergic stabilizers; -MK-801; motor activity; negative symptoms; - -OSU6162; prolactin; rat; schizophrenia; social withdrawal;

   Sammanfattning : Schizophrenia is a severe mental disorder manifested by positive, negative and cognitive symptoms. Current antipsychotic drugs have poor effects on negative and cognitive symptoms, thus necessitating the development of new antipsychotic treatments. Dopaminergic stabilizers constitute a novel concept for the treatment of schizophrenia. LÄS MER

5. 4. Non-motor symptoms in Parkinson’s disease : modeling and mechanisms

   Författare :Débora Masini; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Parkinson’s disease (PD) is a common neurodegenerative disorder, typically characterized by the progressive death of midbrain dopaminergic neurons projecting from the substantia nigra to other areas within the basal ganglia. Historically, PD has been diagnosed as a purely motor disorder dominated by bradykinesia (slowness of movement), rigidity, resting tremor, and postural instability. LÄS MER

7. 5. Gastrointestinal symptoms in chronic renal failure. Prevalence and pathophysiological mechanisms

   Författare :Hans Strid; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic renal failure; end-stage renal disease; gastrointestinal symptoms; overuse; proton pump inhibitors; H2-receptor antagonists; quality of life; manometry; small intestinal bacterial overgrowth; gastric emptying; Helicobacter pylori;

   Sammanfattning : Chronic renal failure (CRF) has a varying etiology and is characterised by an increasing accumulation of toxic metabolic waste products in the blood. Malnutrition is a common finding in uraemic patients and is regarded as a marker for morbidity and mortality. Many factors, including gastrointestinal (GI) symptoms, lead to malnutrition in CRF. LÄS MER