Sökning: "monika"

Visar resultat 1 - 5 av 145 avhandlingar innehållade ordet monika.

  1. 1. Uncertainty, variability and environmental risk analysis

    Författare :Monika Filipsson; Tomas Öberg; Bo Bergbäck; Lars Rosén; Linnéuniversitetet; []
    Nyckelord :Contaminated land; exposure assessment; exposure factors; risk analysis; risk perception; uncertainty; variability; probabilistic risk assessment; NATURAL SCIENCES; NATURVETENSKAP; Miljövetenskap; Environmental Science;

    Sammanfattning : The negative effects of hazardous substances and possible measures that can be taken are evaluated in the environmental risk analysis process, consisting of risk assessment, risk communication and risk management. Uncertainty due to lack of knowledge and natural variability are always present in this process. LÄS MER

  3. 2. Thyroid hormones and their receptors in transcriptional regulation

    Författare :Monika Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Thyroid hormone receptor; regulatory response element; palindrome; directrepeat; everted repeat; DNA hinding domain; P75gag-v-erbA; differentiation; nuclearlocalization; repression.;

    Sammanfattning : The thyroid hormone receptors (TRs) are encoded by two genes, alpha and ß, and belong to a family of hormone activated nuclear receptors. This family includes the receptors for retinoids and vitamin D3 as well as the receptors for steroid hormones. LÄS MER

  4. 3. Endothelial dysfunction in the pulmanory circulation after cardiopulmonary bybass : with special reference to the reactivity to acetylcholine

    Författare :Monika Angdin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acetylcholine; acetylcysteine; allopurinol; antioxidants; cardiopulmonary bypass; heart surgery; L-arginine; nitric oxide; pulmonary circulation; reperfusion injury; vascular resistance; vitamin C; vitamin E.;

    Sammanfattning : The endothelium is important as a physical barrier between the bloodstream and the body tissues. It also plays an important role in the control of vasomotor tone, coagulation, and for the interaction between the vessel wall, leukocytes and platelets. One of the most important regulators released from the endothelium is nitric oxide (NO). LÄS MER

  5. 4. Clinical management of pancreatic cancer aided by histone signatures

    Författare :Monika Bauden; Lund Kirurgi; []
    Nyckelord :Pancreatic cancer; Histone modifications; Tumor size; Biomarkers; Tumor; LC MS MS; Nucleosomics; Histone H1.3;

    Sammanfattning : .... LÄS MER

  7. 5. Understanding the role of bone marrow niche in myeloid malignancies

    Författare :Monika Dolinska; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Normal hematopoiesis is generated and maintained by rare hematopoietic stem cells (HSCs) through their capacity to self-renew and differentiate. This process is rigorously controlled, both by HSC-intrinsic molecular programs and extrinsic signals emitted by the local bone marrow (BM) microenvironment, the so-called HSC niche. LÄS MER