Sökning: "acetylcysteine"

Visar resultat 1 - 5 av 40 avhandlingar innehållade ordet acetylcysteine.

  1. 1. Effect of Ischaemia-Reperfusion on Rabbit Kidney and Human Brain

    Författare :Jagdish Shivlal Gondalia; Göteborgs universitet; []
    Nyckelord :Free radicals; ischaemia-reperfusion; cell bioenergetics; NMR; ESR; carotid artery stenosis; endarterectomy; allopurinol; acetylcysteine; MMP-1; ICAM-1; MCP-9; oxLDL;

    Sammanfattning : Free radicals are produced in various organs at ischaemia-reperfusion. The final stage in radical damage is lipid peroxidation. We have demonstrated previously that a lipid-soluble antioxidant improves restoration of bioenergetics in rabbit kidneys after ischaemia, as reflected in 31P spectrometry. LÄS MER

  3. 2. Chloride transport and inflammation in cystic fibrosis airways

    Författare :Georgia Varelogianni; Godfried Roomans; Marie Johannesson; Ólafur Baldersson; Örebro universitet; []
    Nyckelord :Cystic fibrosis; CFTR; chloride efflux; N-acetylcysteine; ambroxol; duramycin; Nod-like receptors; cytokines; Medicin; Medicine;

    Sammanfattning : Cystic fibrosis (CF) is one of the most common lethal, autosomal recessive inherited diseases among Caucasians. It is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), a chloride channel activated by cyclic AMP. LÄS MER

  4. 3. Advances in Pharmacological Treatment of Cystic Fibrosis

    Författare :Igor Oliynyk; Godfried M. Roomans; Marie Johannesson; Hugo R. de Jonge; Örebro universitet; []
    Nyckelord :Cystic fibrosis; CFTR; chloride transport; N-acetylcysteine; NO-donors; duramycin; intracellular calcium; azithromycin; MEDICINE; MEDICIN; Medicin; Medicine;

    Sammanfattning : Cystic fibrosis (CF) is an inborn, hereditary disease, due to mutations in the gene for a cAMP-activated chloride (Cl-) channel, the cystic fibrosis transmembrane conductance regulator (CFTR). As a result of impaired ion and water transport,the airway mucus is abnormally viscous, which leads to bacterial colonization. LÄS MER

  5. 4. Adipose tissue mitchondrial function is modulated by antioxidants

    Författare :Eduard Peris Franquet; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocyte; metabolism; browning; antioxidant; mitochondria; oxidative stress; adrenergic recpetor; N-acetylcysteine; glutathione; reactive oxygen species;

    Sammanfattning : Antioxidants are widely used as reactive oxygen species (ROS) scavenging agents in experimental research and in conditions where oxidative stress plays a primary role. However, the effect of antioxidant supplementation on white and brown adipose tissue functionality is understudied, and the role of ROS and/or antioxidant treatment during adipose tissue browning, a process in which the adipocytes’ mitochondrial density and activity increase, is largely unknown. LÄS MER

  7. 5. Intestinal permeability : a parameter of mucosal dysfunction

    Författare :Pål Lundin; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Peptide; N-acetylcysteine; Medium-chain glyceride; Mannitol; Macromolecules; Lipid; Kinetics; In vivo; In vitro; In situ; Intestine; Injury; Inflammation; HLA-B27; HCl; Epithelium; Enhancer; dDAVP; 51Cr-EDTA; BSA; Absorption; Albumin; Permeability; Animal physiology; Djurfysiologi;

    Sammanfattning : The gastrointestinal tract has two opposing functions; to absorb nutrients and electrolytes, and to act as a barrier towards hazardous and non-nutritional substances. In the present thesis the barrier function of the gastrointestinal tract was studied in animal models in vivo, in situ and in vitro. LÄS MER