Sökning: "mixed methods"

Visar resultat 21 - 25 av 1122 avhandlingar innehållade orden mixed methods.

1. 21. Mixed Effects Modeling of Deterministic and Stochastic Dynamical Systems - Methods and Applications in Drug Development

   Författare :Jacob Leander; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; pharmacometrics; pharmacokinetics; mixed effects; drug development; pharmacodynamics; parameter estimation; time-to-event; mathematical modeling; dynamical systems;

   Sammanfattning : Mathematical models based on ordinary differential equations (ODEs) are commonly used for describing the evolution of a system over time. In drug development, pharmacokinetic (PK) and pharmacodynamic (PD) models are used to characterize the exposure and effect of drugs. LÄS MER

3. 22. Novel Statistical Methods in Quantitative Genetics : Modeling Genetic Variance for Quantitative Trait Loci Mapping and Genomic Evaluation

   Författare :Xia Shen; Örjan Carlborg; Lars Rönnegård; William Hill; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; statistical genetics; quantitative trait loci; genome-wide association study; genomic selection; genetic variance; hierarchical generalized linear model; linear mixed model; random effect; heteroscedastic effects model; variance-controlling genes; Complex Systems – Microdata Analysis;

   Sammanfattning : This thesis develops and evaluates statistical methods for different types of genetic analyses, including quantitative trait loci (QTL) analysis, genome-wide association study (GWAS), and genomic evaluation. The main contribution of the thesis is to provide novel insights in modeling genetic variance, especially via random effects models. LÄS MER

4. 23. Embedding Theorems for Mixed Norm Spaces and Applications

   Författare :Robert Algervik; Viktor Kolyada; Javier Soria; Karlstads universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mixed norms; rearrangements; modulus of continuity; embeddings; Sobolev spaces; Besov spaces; Lorentz spaces; Mathematical analysis; Analys; Matematik; Mathematics;

   Sammanfattning : This thesis is devoted to the study of mixed norm spaces that arise in connection with embeddings of Sobolev and Besov type spaces. We study different structural, integrability, and smoothness properties of functions satisfying certain mixed norm conditions. Conditions of this type are determined by the behaviour of linear sections of functions. LÄS MER

5. 24. Embedding Theorems for Mixed Norm Spaces and Applications

   Författare :Robert Algervik; Viktor Kolyada; Lars-Erik Persson; Karlstads universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mixed norms; embeddings; rearrangements; anisotropic fractional Sobolev spaces; anisotropic Besov spaces; mixade normer; inbäddningar; omarrangeringar; anisotropa fractionära Sobolev rum; anisotropa Besov rum; MATHEMATICS; MATEMATIK; Matematik; Mathematics;

   Sammanfattning : This thesis is devoted to the study of mixed norm spaces that arise in connection with embeddings of Sobolev and Besov type spaces. The work in this direction originates in a paper due to Gagliardo (1958), and was continued by Fournier (1988) and by Kolyada (2005). We consider fully anisotropic mixed norm spaces. LÄS MER

7. 25. Reduction of Substrate Noise in Mixed-Signal Circuits

   Författare :Erik Backenius; Mark Vesterbacka; Kejll O. Jeppson; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Mixed-signal; Substrate noise; Substrate modeling; Simultaneous switching noise; SSN; Digital; Analog; Clock; Electronics; Elektronik;

   Sammanfattning : In many consumer products, e.g., cellular phones and handheld computers, both digital and analog circuits are required. Nowadays, it is possible to implement a large subsystem or even a complete system, that earlier required several chips, on a single chip. LÄS MER