Sökning: "membrane remodeling"

Visar resultat 21 - 25 av 41 avhandlingar innehållade orden membrane remodeling.

1. 21. Profilin : From the Cell Edge into the Nucleus

   Författare :Sara Sadi; Roger Karlsson; Maria Vartiainen; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; profilin; actin; microfilament system; nucleus; SRF; MRTF; MAL; transcription; microtubules; Cell Biology; cellbiologi;

   Sammanfattning : Internal and external signaling dependent changes in cell behavior are directly linked to force-generating remodeling of the actin microfilament system which is juxtaposed to the inside of the plasma membrane. This dynamic filament system is involved in many processes in the cytoplasm and the nucleus of eukaryotic cells. LÄS MER

3. 22. Parathyroid hormone-related protein (PTHrP), calcium and human osteoblast-like cells

   Författare :Jon A Tsai; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :hOB cells; PTHrP; cAMP; IGFs; IGFBPs; IL-1ß; TGF-ß; [Ca 2 ]i; [Ca2 ]O;

   Sammanfattning : Parathyroid hormone-related protein (PTHrP) may cause humoral hypercalcernia of malignancy (HHM) when overproduced by malignant tumors, but is also produced in lower amounts under normophysiological conditions in practically all cell types, including osteoblasts. One of the aims of the present study was to investigate interactions between PTHrP and osteoblasts, to elucidate bone-regulating functions of PTHrP. LÄS MER

4. 23. Resident T cells steer tissue responses in human skin

   Författare :Borislav Ignatov; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The human skin constitutes a biological barrier against threats to the body from the surrounding environment. Tissue-resident memory cells (TRM) reside in the skin and provide local memory of previous encounters with microbes and pathogens, are poised to promptly eliminating infected cells and elicit tissue-wide defense state. LÄS MER

5. 24. Regulation of inflammation and angiogenesis in the cornea

   Författare :Anthony Mukwaya; Neil S Lagali; Beatrice Bourghardt Peebo; Lasse D Jensen; Thomas Ritter; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Inflammation and angiogenesis, the growth of new blood vessels from pre-existing ones, are involved in tumor growth, ocular diseases and wound healing. In ocular angiogenesis, new pathological vessels grow into a specific eye tissue, leak fluid, and disrupt vision. LÄS MER

7. 25. Towards a Refined Model of Neutrophil Motility

   Författare :Vesa-Matti Loitto; Karl-Eric Magnusson; Tommy Andersson; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human polymorphonuclear leukocytes. PMNL; neutrophils; neutrophil motility; N-formyl-Met-Leu-Phe; Medical microbiology; Medicinsk mikrobiologi;

   Sammanfattning : The ability of human polymorphonuclear leukocytes (PMNL; neutrophils), to sense and move to sites of infection is essential for our defense against pathogens. Cell motility is critically dependent on a dynamic remodeling of morphology. LÄS MER