Sökning: "mantle cell lymphoma"

Visar resultat 11 - 15 av 35 avhandlingar innehållade orden mantle cell lymphoma.

  1. 11. Telomere length as prognostic parameter in chronic lymphocytic leukemia

    Författare :Pawel Grabowski; Göran Roos; Ylva Paulsson Karlsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; telomere length; chronic lymphocytic leukemia; prognosis; longitudinal sampling; genomic aberrations; IGHV; CD38; ZAP70; prognostic factors; Pathology; Patologi; patologi; Pathology;

    Sammanfattning : B-cell chronic lymphocytic leukemia (B-CLL) is the most common leukemia among the adult population in western countries and accounts for 30-40% of all leukemias. With survival time ranging from months to decades, the clinical course of individual CLL patients is highly variable. LÄS MER

  3. 12. Transcriptional Analysis of Cell-Sorted B-cell Lymphomas From High-throughput to Focused Identification of Molecular Targets

    Författare :Ulrika Andreasson; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microarray; molecular target; gene expression profiling; B-cell lymphoma; Fluorescence-activated cell sorting;

    Sammanfattning : B cell lymphomas (BCLs) are a group of severe cancers, afflicting both men and women at different ages. Gene expression profiling (GEP), have during the latest decades fundamentally contributed to a better classification and biological understanding of the different BCLs. LÄS MER

  4. 13. Genetic characterization of hematological malignancies with focus on mantle cell lymphoma

    Författare :Emma Flordal Thelander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lymphoid cancer affects about 2000 individuals in Sweden every year. Lymphoma is divided into numerous subclasses based on histopathological and phenotypic characterization, however, for some lymphoma entities, the classification criteria are insufficient and clinical diversity is seen in cases of the same diagnosis. LÄS MER

  5. 14. Immunoglobulin Gene Analysis in Different B cell Lymphomas : With Focus on Cellular Origin and Antigen Selection

    Författare :Mia Thorsélius; Richard Rosenquist Brandell; Christer Sundström; Anders Rosén; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; B cell lymphoma; Immunoglobulin; V gene; somatic hypermutation; antigen selection; quantitative PCR; Genetik; Clinical genetics; Klinisk genetik;

    Sammanfattning : B cell lymphoma (BCL) comprises a biologically and clinically heterogeneous group of tumors deriving from different stages of B cell development. The immunoglobulin (Ig) variable heavy chain (VH) gene rearrangement is unique for each BCL and can be used to reveal cellular origin, to study signs of antigen selection and to quantify tumor cell load. LÄS MER

  7. 15. Biological pathways in B-cell non-Hodgkin's lymphoma

    Författare :Mohit Aggarwal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Non-Hodgkin’s lymphomas have become more prevalent in the past 20 years. They constitute a diverse group of lymphoid tumors that have been understood and classified according to their clinical behaviour, anatomic location, morphology, immunophenotype, cytogenetics, and gene expression profile. LÄS MER