Sökning: "let-7"
Hittade 5 avhandlingar innehållade ordet let-7.
1. The Regulatory Role of microRNAs in the Mouse and Human Brain
Sammanfattning : microRNAs (miRNAs) are 20-24 nucleotides small, single-stranded, non-coding RNAs. They associate with Argonaute (AGO) proteins and exert their function by inhibition or degradation of messenger RNAs. LÄS MER
2. Novel mechanisms in depression: focus on telomere biology and epigenetic regulation
Sammanfattning : Depression is a complex disorder with an average lifetime prevalence from 11.1% to 14.6%. It causes serious disability and is a significant public health problem worldwide. LÄS MER
3. Signaling pathways in Drosophila immunity
Sammanfattning : Drosophila relies on innate immunity to protect itself from its hostile environment throughout its life cycle. Despite the remarkable progress in understanding many aspects of Drosophila immunity, there are still big gaps in our knowledge. LÄS MER
4. CYTOGENETIC AND MOLECULAR GENETIC CHARACTERIZATION OF LIPOMAS
Sammanfattning : The focus of this thesis was to study cytogenetic and molecular genetic aberrations in lipomas. For this purpose, chromosome banding analysis, fluorescence in situ hybridization (FISH), as well as high resolution single nucleotide polymorphism (SNP)–arrays were used to identify recurrent chromosomal aberrations in lipomas. LÄS MER
5. MicroRNAs and their processing factors in Caenorhabditis elegans and human cancers
Sammanfattning : MicroRNAs (miRNAs) are small noncoding RNAs approximately 20-22 nucleotides (nt) long. These small RNAs (sRNAs) was initially discovered in Caenorhabditis elegans (C. elegans), but is conserved in over 50 animal species. LÄS MER