Sökning: "cytogenetic"
Visar resultat 1 - 5 av 94 avhandlingar innehållade ordet cytogenetic.
1. CYTOGENETIC AND MOLECULAR GENETIC CHARACTERIZATION OF LIPOMAS
Sammanfattning : The focus of this thesis was to study cytogenetic and molecular genetic aberrations in lipomas. For this purpose, chromosome banding analysis, fluorescence in situ hybridization (FISH), as well as high resolution single nucleotide polymorphism (SNP)–arrays were used to identify recurrent chromosomal aberrations in lipomas. LÄS MER
2. Genetic analyses of multiple myeloma and related plasma cell dyscrasias
Sammanfattning : Acquired genetic changes have proved to be of diagnostic and prognostic importance in different hematologic malignancies as well as in some solid tumor types. However, although multiple myeloma (MM), an incurable disease, and its proceeding stage monoclonal gammopathy of undetermined significance (MGUS) are quite common, little is known about the karyotypic features of these plasma cell dyscrasias. LÄS MER
3. Case-control studies on risk factors for myeloid leukemias and myelodysplastic syndromes
Sammanfattning : Case-control studies comprising telephone interviews for 333 cases of acute myeloid leukemia (AML), 226 cases of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), 330 cases of myelodysplastic syndromes (MDS), and matched controls were conducted. Information had to be obtained from next-of-kin much more often for cases (85%) than for controls (18%). LÄS MER
4. Cytogenetic studies of benign breast lesions
Sammanfattning : In the present thesis benign breast lesions of various histologies, i.e. LÄS MER
5. Clinical - cytogenetic correlations in malignant hematologic disorders
Sammanfattning : In the present thesis, clinicogenetic correlations are investigated in a large population-based series of acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), acute lymphoblastic leukemia, and chronic myeloid leukemia, for which the karyotypes were analyzed at the same center. The karyotypic pattern, i.e. LÄS MER