Sökning: "NFκB"

Visar resultat 1 - 5 av 39 avhandlingar innehållade ordet NFκB.

  1. 1. Signal Transduction in Malignant Cells – Transformation, Activation and Differentiation

    Författare :Karin Kårehed; Fredrik Öberg; Jan-Ingvar Jönsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; transformation; PDGF; PI3K; Rho-GTPase; U-937; FcγRI; macrophage; Stat1; PKR; NFκB; ATRA; differentiation; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Pathology; Patologi;

    Sammanfattning : All aspects of cell life are regulated by signal transduction mechanisms. This thesis describes the regulatory roles of a few key signal transduction molecules involved in three major biological responses. LÄS MER

  3. 2. Arsenic Influences Virus Replication in Experimental Coxsackievirus B3 Infection

    Författare :Ylva Molin; Nils-Gunnar Ilbäck; Eva Hjelm; Göran Friman; Jonas Blomberg; Gunnar Nordberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coxsackievirus B3; trace elements; arsenic; selenium; virology; IFN-γ; NFκB; Infectious diseases; Infektionssjukdomar; Infectious Diseases; Infektionssjukdomar;

    Sammanfattning : Trace elements are essential for the host defence against infections, and during common infections, the balance of trace elements is changed in serum and tissues. Supplementation with selenium (Se), an essential trace element, is known to decrease the severity of coxsackievirus B3 (CVB3) infection in mice. LÄS MER

  4. 3. Molecular mechanisms of zebrafish sex differentiation and sexual behavior

    Författare :Ajay Pradhan; Per-Erik Olsson; Jana Jass; Svante Winberg; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NFκB; prostaglandin; retinoic acid; gonads; gene regulation; brain; Molecular Biology; Molekylärbiologi;

    Sammanfattning : .... LÄS MER

  5. 4. Signaling pathways in Drosophila immunity

    Författare :Shiva Seyedoleslami Esfahani; Ylva Engström; Steven Wasserman; Stockholms universitet; []
    Nyckelord :Drosophila immunity; signaling pathways; Cactus; NFκB; Molecular Biology; molekylärbiologi;

    Sammanfattning : Drosophila relies on innate immunity to protect itself from its hostile environment throughout its life cycle. Despite the remarkable progress in understanding many aspects of Drosophila immunity, there are still big gaps in our knowledge. LÄS MER

  7. 5. Inflammatory cytokines and NFκB in Alzheimer’s disease

    Författare :Linda Fisher; Kerstin Iverfeldt; Illana Gozes; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-amyloid; interleukin-1; interleukin-6; cell-penetrating peptide; PNA; Neurochemistry; Neurokemi;

    Sammanfattning : Alzheimer’s disease is the most common form of dementia. It is a neurodegenerative disorder characterized by extracellular senile plaques and intracellular neurofibrillary tangles. The main constituent of the senile plaques is the neurotoxic β-amyloid peptide. LÄS MER