Sökning: "in situ hybridization"

Visar resultat 31 - 35 av 298 avhandlingar innehållade orden in situ hybridization.

  1. 31. Maternal milk feedings and cytomegalovirus infection in preterm infants in Sweden

    Författare :Soley Omarsdottir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In Sweden, preterm infants are preferably fed human milk. Very preterm infants (< 32 weeks), who are unable to breastfeed, are fed with expressed maternal milk via a nasogastric tube. Mothers of these infants often experience difficulties in establishing and maintaining lactation. LÄS MER

  2. 32. Fluorescence in situ hybridization for the detection of genetic alterations in prostate and bladder malignancies : significance as a genetic marker to predict the patient prognosis

    Författare :Hideyasu Matsuyama; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :prostate cancer bladder cancer tumor suppressor gene chromosomal deletion chromosome 8p; chromosome lOq chromosome 16q; fluorescence in situ hybridization Prostate cancer and bladder cancer are common urological malignancies in man; while a lack of;

    Sammanfattning : Prostate cancer and bladder cancer are common urological malignancies in man, while a lack of basic information underlying the oncogenesis and the tumor progression makes it difficult to form therapeutic strategies against these malignancies. Recent advances of molecular biology revealed that genetic alteration play a crucial role in the oncogenesis and progression of these tumors. LÄS MER

  3. 33. Studies on cytokine mRNA expression in mononuclear cells in neuroimmunological diseases

    Författare :Darius Matusevicius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS), characterized by perivascular accumulation of blood mononuclear cells (MNC) and patchy demyelination. High levels of circulating myelin antigen specific T and B cells, with an accumulation in cerebrospinal fluid (CSF), suggest the involvement of cytokines in the pathogenesis of MS. LÄS MER

  4. 34. Inflammation and immunothrombosis in cerebral cavernous malformation : Novel molecular targets for the treatment of an incurable disease

    Författare :Maria Ascención Globisch; Peetra Magnusson; Elisabetta Dejana; Marie Jeansson; Anna Randi; Uppsala universitet; []
    Nyckelord :Cavernoma; Inflammation; Coagulation; Blood-brain-barrier; Blood; Hypoxia; Propranolol; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology;

    Sammanfattning : Cerebral cavernous malformation (CCM) is a vascular disease that causes mulberry-like lesions (cavernomas) in the central nervous system (CNS). Cavernomas are fragile, leaky and prone to rupture which may cause symptoms such as epileptic seizures, focal neurological deficits and hemorrhagic strokes. CCM lesions can appear sporadically in 0. LÄS MER

  5. 35. Matrix metalloproteinases and their inhibitors in ocular neovascularization

    Författare :Björn Steén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Angiogenesis; Neovascularization; Retina; Bruch membrane; Cornea; MMP; TIMP; VEGF; In situ hybridization.;

    Sammanfattning : Growth of pathological new vessels (angiogenesis) in the eye is a leading cause of severe vision-loss. Ocular angiogenesis is seen in the anterior part of the eye as in corneal neovascularization, or in the posterior part as in diabetic retinopathy, retinopathy of prematurity or age-related macular degeneration. LÄS MER