Sökning: "prostate cancer bladder cancer tumor suppressor gene chromosomal deletion chromosome 8p"

Hittade 2 avhandlingar innehållade orden prostate cancer bladder cancer tumor suppressor gene chromosomal deletion chromosome 8p.

1. 1. Molecular cytogenetic investigations of chromosomal abnormalities in prostate and urinary bladder cancers

   Författare :Yi Pan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :prostate cancer; bladder cancer; FISH; SKY;

   Sammanfattning : Tumorigenesis is suggested to be caused by base pair mutations and chromosomal abnormalities leading to inactivation of tumor suppressor genes an activation of oncogenes. However, still it is not clear for the vast majority of these changes how they contribute to the tumorigenesis of the prostate and bladder cancers. LÄS MER

3. 2. Fluorescence in situ hybridization for the detection of genetic alterations in prostate and bladder malignancies : significance as a genetic marker to predict the patient prognosis

   Författare :Hideyasu Matsuyama; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :prostate cancer bladder cancer tumor suppressor gene chromosomal deletion chromosome 8p; chromosome lOq chromosome 16q; fluorescence in situ hybridization Prostate cancer and bladder cancer are common urological malignancies in man; while a lack of;

   Sammanfattning : Prostate cancer and bladder cancer are common urological malignancies in man, while a lack of basic information underlying the oncogenesis and the tumor progression makes it difficult to form therapeutic strategies against these malignancies. Recent advances of molecular biology revealed that genetic alteration play a crucial role in the oncogenesis and progression of these tumors. LÄS MER