Sökning: "Elisabetta Dejana"

Hittade 2 avhandlingar innehållade orden Elisabetta Dejana.

1. 1. Inflammation and immunothrombosis in cerebral cavernous malformation : Novel molecular targets for the treatment of an incurable disease

   Författare :Maria Ascención Globisch; Peetra Magnusson; Elisabetta Dejana; Marie Jeansson; Anna Randi; Uppsala universitet; []
   Nyckelord :Cavernoma; Inflammation; Coagulation; Blood-brain-barrier; Blood; Hypoxia; Propranolol; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology;

   Sammanfattning : Cerebral cavernous malformation (CCM) is a vascular disease that causes mulberry-like lesions (cavernomas) in the central nervous system (CNS). Cavernomas are fragile, leaky and prone to rupture which may cause symptoms such as epileptic seizures, focal neurological deficits and hemorrhagic strokes. CCM lesions can appear sporadically in 0. LÄS MER

3. 2. Modulation of Angiogenesis by Laminins and Heparan Sulfate

   Författare :Lars Jakobsson; Lena Claesson-Welsh; Johan Kreuger; Elisabetta Dejana; Uppsala universitet; []
   Nyckelord :Molecular medicine; Embryonic stem; heparan sulfate; laminin; basement membrane; VEGFR-2; VEGF; endothelial cell; signaling; angiogenesis; vasculogenesis; embryoid body; Molekylärmedicin;

   Sammanfattning : Blood vessels transport blood with essential nutrients and oxygen to the cells in our body. In a healthy adult, formation of new vessels (angiogenesis) occurs only in case of tissue repair and growth. LÄS MER