Sökning: "immune sera immunology"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden immune sera immunology.

1. 1. Regulatory immune responses in humans naturally primed to Plasmodium falciparum or vaccinated with tetanum toxoid or purified protein derivative

   Författare :Gehad Elghazali; Thor Grundtvig Theander; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

   Sammanfattning : It is well established that the balance between functionally distinct regulatory CD4+ T cells plays a major role in the development of immunity and/or pathogenesis to many different infections. In spite of the importance of Th lineage commitment in disease, the critical questions how the balance between Th1 and Th2 cells is regulated is largely unresolved. LÄS MER

3. 2. Vaccine development strategies applied to the Plasmodium falciparum malaria antigen 332

   Författare :Nina-Maria Vasconcelos; Klavs Berzins; Matti Sällberg; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; malaria; sub-unit vaccines; immunogenicity; antibody response; antigen Pf332; Immunology; Immunologi;

   Sammanfattning : Malaria is one of the major infectious diseases in the world with regard to mortality and morbidity, and the development of a vaccine against the malaria parasite Plasmodium falciparum is considered of high priority. The aim of the work presented in this thesis was to develop and characterize recombinant vaccine constructs based on the P. LÄS MER

4. 3. The role of natural killer cells and inflammatory mediators in preeclamptic pregnancies

   Författare :Nora Bachmayer; Eva Sverremark-Ekström; Katarina Bremme; Lucia Mincheva-Nilsson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; preeclampsia; NK cells; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : The maternal immune system must be able to adjust during pregnancy and accept the foetus that expresses paternal antigens. These changes are found both in placenta and circulation, including a mild inflammatory response. NK cells are abundant during the early part of pregnancy in placenta and are thought to be important for placental development. LÄS MER

5. 4. Immunological and functional properties of a non-repeat region in Plasmodium falciparum antigen Pf155/RESA

   Författare :Siddique Abu Bakar; Lars Hvid; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

   Sammanfattning : Plasmodium falciparum malaria is one of the most prevalent of all the great insect-borne diseases causing high morbidity and mortality in humans. As conventional anti-malarial treatment is becoming increasingly inefficient, alternative approaches to combat the parasite, like vaccine development, are of high priority. LÄS MER

7. 5. Aspects of inflammation, angiogenesis and coagulation in preeclampsia

   Författare :Roland Boij; Leif Matthiesen; Jan Ernerudh; Maria Jenmalm; Göran Berg; Henrik Hagberg; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Preeclampsia is a major challenge to obstetricians, due to its impact on maternal and fetal morbidity and mortality and the lack of preventive and treatment strategies. The overall aim of this thesis is to increase the knowledge of the pathogenesis of preeclampsia including the role of inflammation, angiogenesis and coagulation, both locally at the fetomaternal interface and in the maternal circulation. LÄS MER