Sökning: "hypercoagulable state"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden hypercoagulable state.

  1. 1. Arterial Thrombosis in Factor V Leiden or Activated Protein C Resistance. Clinical and Experimental Studies

    Författare :Ellis Sampram; Malmö Klinisk koagulationsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Activated protein c resistance; Factor V Leiden mutation; thrombophilia; hypercoagulable state; Factor V Leiden mice; arterial thrombosis; venous thromboembolism; peripheral vascular reconstructions; peripheral vascular reconstruction occlusion;

    Sammanfattning : Abstract The last two decades has seen an avalanche of studies establishing Activated protein C (APC) resistance due to Factor V Leiden mutation as the most prevalent genetic risk factor, yet known, for venous thromboembolism. This has been documented in 20-60% of patients with deep vein thrombosis (DVT). LÄS MER

  2. 2. Troponin elevation in acute stroke : clinical characteristics and the link to cancer-associated neutrophil extracellular traps

    Författare :Charlotte Thålin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Elevated plasma levels of troponin, a marker of myocardial injury, are a frequent observation in stroke patients. Despite several reports on an adverse short-term prognosis, however, the significance of troponin elevation in stroke is still controversial, and the myocardial injury often lacks a clear etiology. LÄS MER

  3. 3. Resistance to activated protein C a novel risk factor for venous thrombosis

    Författare :Peter Svensson; Malmö Klinisk koagulationsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APC resistance; mutation; venous thrombosis; blood coagulation; Protein C; factor V; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Sammanfattning : Activated protein C resistance (APC resistance) is the most common hereditary condition associated with venous thrombosis. The syndrome known as APC resistance is perfectly linked to a mutation in the gene coding coagulation FV (FV:Q506) mutation changing Arg 506 to Gln in the APC cleavage site. LÄS MER

  4. 4. Hypercoagulation in preeclampsia : implications for maternal health and foetal growth

    Författare :Shu He; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Background. Preeclampsia (PE) is a serious complication of pregnancy characterized by hypertension, proteinuria, oedema and hypercoagulation. Damage in organs, such as the liver and kidney, is harmful to the maternal health. Impairments in placental function cause intrauterine growth retardation (IUGR). LÄS MER

  5. 5. Effects of combined oral contraceptives on hemostasis and biochemical risk indicators for venous thromboembolism and atherothrombosis

    Författare :Marianne van Rooijen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Combined oral contraceptives; emergency contraception; menstrual cycle; ethinylestradiol; levonorgestrel; desogestrel; lipoproteins; hemostasis; risk indicators; APC resistance; SHBG;

    Sammanfattning : Combined oral contraceptives (COCs) are one of the most common contraceptive methods in the world. Already a few years after their introduction, in the early 1960s, case reports were published showing associations between use of COCs and venous and arterial thromboembolism. LÄS MER