Sökning: "human leucocyte antigen"

Hittade 5 avhandlingar innehållade orden human leucocyte antigen.

1. 1. Early life dietary factors on the risk of celiac disease. Associations of dietary factors with risk of celiac disease in children at genetic risk

   Författare :Elin M Hård af Segerstad; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Celiac Disease; Celiac disease autoimmunity; Gluten; Nutrition epidemiology; Dietary Intake; Children’s health; human leucocyte antigen; Transglutaminase Antibodies; The Environmental Determinants of Diabetes in the Young TEDDY ; Dietary patterns; Milk powder; Gluten-containing grains; Food records;

   Sammanfattning : .... LÄS MER

3. 2. Genetic studies of complex autoimmune disease

   Författare :Alexandra Gyllenberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : In complex autoimmune diseases, there are both genetic and environmental factors that influence our immune system and contribute to the development of disease. The pathways, interactions and mode of inheritance are difficult to unravel, and many discoveries are yet to be done. LÄS MER

4. 3. Genetic variation of tight junction structures in intestinal inflammation

   Författare :Elisabeth Norén; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The epithelial barrier facing the external environment in the gastrointestinal (GI) tract is comprised of several components, including the tight junction (TJ) structures observed for the first time in 1963. TJ structures, which are multiprotein complexes composed of transmembrane proteins and a diverse spectrum of intracellular components, create a primary barrier to diffusion of ions, solutes, and water and they concomitantly prevent permeation of pro-inflammatory factors, such as pathogens, toxins, and antigens. LÄS MER

5. 4. Aspects of beta cell and thyroid autoimmunity in children

   Författare :Bengt Lindberg; Pediatrisk endokrinologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; virus; vaccination; type 1 diabetes mellitus; thyroiditis; allergy; autoantibodies; Pediatri;

   Sammanfattning : The two most common autoimmune endocrine diseases in children are autoimmune thyroiditis (AIT) and Type 1 (insulin-dependent) diabetes mellitus (IDDM). Autoantibodies (ab) can be found several years before clinical diagnosis in both diseases. LÄS MER

7. 5. Perinatal risk factors for type 1 diabetes in children and adolescents

   Författare :Nina Lindell; Ulf Samuelsson; Ann Josefsson; Annelie Carlsson; Mikael Knip; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Background Type 1 diabetes (T1D) is an autoimmune disease characterized by progressive loss of the insulin producing pancreatic β-cells. The disease process starts years before the clinical diagnosis. The cause of T1D is unknown, but it is believed to be a combination of genetic and environmental factors. LÄS MER