Sökning: "histamine provocation"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden histamine provocation.

  1. 1. Effects of Motion Sickness on Human Thermoregulatory Mechanisms

    Författare :Gerard Nobel; Ola Eiken; Nigel A.S. Taylor; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Motion Sickness; autonomic thermoregulation; behavioural thermoregulation; hypothermia; acetylcholine; histamine; Physiology; Fysiologi;

    Sammanfattning : The presented studies were performed to investigate the effects of motion sickness (MS) on human autonomic and behavioural thermoregulatory mechanisms during cold stress and in a thermoneutral environment. The roles of histaminergic and cholinergic neuron systems in autonomic thermoregulation and MS-dependent dysfunction of autonomic thermoregulation were studied using a histamine-receptor blocker, dimenhydrinate (DMH), and a muscarine-receptor blocker, scopolamine (Scop). LÄS MER

  3. 2. Nasal mucosal reactivity after long-time exposure to building dampness

    Författare :Stig Rudblad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Indoor environment; histamine provocation; nasal mucosa; mucosal reactivity; rhinostereometry; moisture; Laser-Doppler.;

    Sammanfattning : An association between working and/or residing in damp buildings and respiratory health has been reported in a number of studies. A major limitation has been difficulty in objectively verifying any effects on the mucous membranes of the respiratory tract in order to explain symptoms of irritated eyes, nasal congestion and cough that are often reported by occupants in buildings with indoor air problems. LÄS MER

  4. 3. Allergen-induced late airways reaction in the pig : influence of endogenous and exogenous glucocorticoids

    Författare :Cecilia Fornhem; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ascaris suum; bronchial circulation; bronchial provocation test; budesonidecortisol; leukotrienes; eosinophil peroxidase; eosinophils; histamine; immunohistochemistry; metyrapone; minipig; myeloperoxidase; neutrophils; pig.;

    Sammanfattning : A novel model for studies of the allergen-induced late reaction in the lower airways was developed in the pig. The influence on late bronchial obstruction and granulocyte function of endogenous cortisol levels and treatment with the glucocorticoid budesonide (BUD) was evaluated. LÄS MER

  5. 4. Mast cell activation in response to osmotic and immunological stimulation with focus on release of eicosanoid mediators

    Författare :Magdalena Gulliksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Exercise-induced bronchoconstriction; cyclooxygenase; cord blood derived mast cells; mannitol; prostaglandin D2; leukotriene C4; leukotriene E4; histamine and 15-lipoxygenase.;

    Sammanfattning : Mast cells are important in asthma and other inflammatory diseases. Subjects with asthma have been found to have an increased number of mast cells in their airway smooth muscle and this was related to airway sensitivity. LÄS MER

  7. 5. Cutaneous microdialysis : a technique for human in vivo sampling

    Författare :Thomas Andersson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Microdialysis enables in vivo sampling of endogenous and exogenous substances in the interstitial fluid. A probe equipped with a tubular semi-permeable dialysis membrane is inserted into the skin, and perfused with a physiological solution. LÄS MER