Sökning: "genetic code"

Visar resultat 6 - 10 av 73 avhandlingar innehållade orden genetic code.

  1. 6. Modelling and genetic correction of liver genetic diseases

    Författare :Mihaela Zabulica; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The urea cycle is a set of biochemical reactions that converts highly toxic ammonia into urea for excretion. Deficiencies in any of the genes of the cycle can be life-threatening, with liver transplantation currently being the only definitive treatment. LÄS MER

  3. 7. Inference of Hierarchical Structure in Complex Systems

    Författare :Olof Görnerup; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; Substitution groups; Modularity; Hierarchical dynamics; RNA world; Genetic code; Aggregation; Primordial evolution; Molecular evolution; Model reduction; Self-organization; Lumping; Emergence; Coarse graining;

    Sammanfattning : Hierarchical organization is a central property of complex systems. It is even argued that a system is required to be hierarchical in order to evolve complexity within reasonable time. A hierarchy of a system is defined as the set of self-contained levels at which the system operates and can be described on. LÄS MER

  4. 8. Accuracy of mRNA Translation in Bacterial Protein Synthesis

    Författare :Jingji Zhang; Måns Ehrenberg; Olke C. Uhlenbeck; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein synthesis; genetic code; misreading; error hot spots; kinetics; aminoglycoside; Biokemi; Biochemistry;

    Sammanfattning : Reading of messenger RNA (mRNA) by aminoacyl-tRNAs (aa-tRNAs) on the ribosomes in the bacterial cell occurs with high accuracy. It follows from the physical chemistry of enzymatic reactions that there must be a trade-off between rate and accuracy of initial tRNA selection in protein synthesis: when the current accuracy, the A-value, approaches its maximal possible value, the d-value, the kinetic efficiency of the reaction approaches zero. LÄS MER

  5. 9. Health Monitoring for Aircraft Systems using Decision Trees and Genetic Evolution

    Författare :Mike Gerdes; Diego Galar; Uday Kumar; Dieter Scholz; Piotr Bilski; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Condition Monitoring; Remaining Useful Life Prediction; Decision Tree; Genetic Algorithm; Fuzzy Decision Tree Evaluation; System Monitoring; Aircraft Health Monitoring; Feature Extraction; Feature Selection; Data Driven; Health Prognostic; Knowledge Based System; Supervised Learning; Data-Driven Predictive Health Monitoring; Health Indicators; Machine Learning; Big Data; Pattern Recognition; Drift och underhållsteknik; Operation and Maintenance;

    Sammanfattning : Reducing unscheduled maintenance is important for aircraft operators. There are significant costs if flights must be delayed or cancelled, for example, if spares are not available and have to be shipped across the world. LÄS MER

  7. 10. Functional analysis of genetic risk markers

    Författare :Jesper Robert Gådin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Regulatory variants are the main factors responsible for genetic predisposition to how e.g. humans react differently to the environment. LÄS MER