Sökning: "gene expression data"

Visar resultat 1 - 5 av 1025 avhandlingar innehållade orden gene expression data.

  1. 1. Statistical analysis of gene expression data

    Författare :Erik Kristiansson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene expression; DNA microarrays; linear models; empirical Bayes; quality control; gene regulation; categorical data analysis; logistic regression; heavy metal stress; ecotoxicology; gene expression;

    Sammanfattning : Microarray technology has become one of the most important tools for genome-wide mRNA measurements. The technique has been successfully applied to many areas in modern biology including cancer research, identification of drug targets, and categorization of genes involved in the cell cycle. LÄS MER

  3. 2. Contributions to Statistical Analysis of Gene Expression Data

    Författare :Anders Sjögren; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA microarray; differential expression; gene regulation; variance stabilising transformation; permutation; reference gene; housekeeping gene; bootstrap; quality control QC ; quality assurance QA ; quality assessment; empirical Bayes; weighted moderated t-statistic; WAME; DNA microarray;

    Sammanfattning : .... LÄS MER

  4. 3. Nonlinear dimensionality reduction of gene expression data

    Författare :Jens Nilsson; Matematik LTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Gene expression; Manifold learning; Nonlinear dimensionality reduction; Microarray;

    Sammanfattning : Using microarray measurements techniques, it is possible to measure the activity of genes simultaneously across the whole genome. Since genes influence each others activity levels through complex regulatory networks, such gene expression measurements are state samples of a dynamical system. LÄS MER

  5. 4. Network and gene expression analyses for understanding protein function

    Författare :Oliver Frings; Erik Sonnhammer; Rune Linding; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biological networks; network inference; network analysis; clustering; network module; network crosstalk; expression analysis; gene signature; biomarker; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Sammanfattning : Biological function is the result of a complex network of functional associations between genes or their products. Modeling the dynamics underlying biological networks is one of the big challenges in bioinformatics. LÄS MER

  7. 5. Statistics in Gene Expression, Metabolomics, and Comparative Genomics in Evolution

    Författare :Alexandra Jauhiainen; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Gene Expression; Metabolomics; Data Integration; Comparative genomics; Gene Expression;

    Sammanfattning : This thesis contains four papers concerning (I) the evolutionary conservation of drug targets and its potential use in environmental risk assessments, (II) RNA degradation as a control mechanism during osmotic stress in the yeast S. cerevisiae, (III) the localization and effects of the gene DDIT3 encoding a key regulator of stress response, and (IV) the integration and analysis of transcriptional and metabolic data to identify active metabolic pathways. LÄS MER