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Visar resultat 1 - 5 av 11 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Prognostic role of the tumour microenvironment in esophago-gastric, pancreatic and periampullary adenocarcinoma: B cells and beyond

    Författare :Richard Fristedt; Tumörmikromiljö; []
    Nyckelord :Polymeric immunoglobulin receptor; B cells; Plasma cells; Esophageal adenocarcinoma; gastric adenocarcinoma; Pancreatic ductal adenocarcinoma; Periampullary adenocarcinoma; Prognosis and survival; Immune system;

    Sammanfattning : Cancer development depends on cells aquiring a skillset of limitless growth and finally invasive properties to allow for metastasis, as summarised by the six hallmarks of cancer. Recently four more hallmarks have been added: genomic instability, deregulating cellular metabolism, tumour-promoting inflammation and avoiding immune destruction. LÄS MER

  3. 2. Regulatory Functions of Protein Phosphorylation in Plant Photosynthetic Membranes

    Författare :Rikard Fristedt; Alexander Vener; Thomas Pfannschmidt; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Oxygenic photosynthesis is the process in plants, algae and cyanobacteria which converts light energy from the sun into carbohydrates and at the same time produces oxygen from water. Both carbohydrates and oxygen are essential to sustain life on earth. LÄS MER

  4. 3. Occupational participation through community mobility among older men and women

    Författare :Sofi Fristedt; Torbjörn Falkmer; Jan Lexell; Jönköping University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The overall aim of the present thesis was to explore and characterise occupational participation and community mobility from an occupational perspective of health and well-being, and to elucidate potential barriers and facilitators for occupational participation and community mobility in older men and women.In Study I, questionnaires were sent to a sample of older citizens (75+) in three Swedish mid-sized municipalities. LÄS MER

  5. 4. Tumour Survival Signals and Epigenetic Gene Silencing in Multiple Myeloma : Implications for Biology and Therapy

    Författare :Charlotte Fristedt Duvefelt; Helena Jernberg-Wiklund; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple myeloma; Polycomb; apoptosis; cIAP2; IAP-inbibitors; proteasome inhibitors; LBH589; PPP; DZNep;

    Sammanfattning : This thesis is focused on multiple myeloma (MM), a haematological malignancy that still remains incurable. The pathogenesis of MM is not fully understood and there is a large intra-tumour and interclonal genetic variation in MM patients. LÄS MER

  7. 5. Motionally induced voltages in near-shore environments : stratified flows, hydraulics and turbulence

    Författare :Tim Fristedt; Matti Leppäranta; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Meteorology; Meteorologi; meteorologi; Meteorology;

    Sammanfattning : .... LÄS MER