Sökning: "Immune system"

Visar resultat 1 - 5 av 1240 avhandlingar innehållade orden Immune system.

  1. 1. The Immune System in the Oldest-Old Clinical and Immunological Studies in the NONA Immune Cohort

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Bengt-Olof Nilsson; Jan Ernerudh; Anders Wikby; Sture Löfgren; Karlis Pauksens; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Elderly; selection; health status; lymphocyte subsets; CD8; CMV; cytomegalovirus; immune risk; immune risk phenotype; IRP; T-cells; interleukin 6; IL-6; survival; mortality; antinuclear antibodies; ANA; ageing; immunosenescence; MEDICINE; MEDICIN;

    Sammanfattning : The oldest-old (people aged 80 or older) constituted 5 % of the population in Sweden in 2000, an increase from 1.5 % fifty years earlier. The immune system undergoes dramatic changes at high age, sometimes referred to as “immunosenescence”. LÄS MER

  2. 2. Leishmaniasis in Sweden. Molecular, diagnostic and epidemiological studies of the parasite Leishmania in a non-endemic country

    Detta är en avhandling från Lund University: Faculty of Medicine

    Författare :Sara Karlsson Söbirk; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; leishmaniasis; Parasite; Epidemiological studies; Serology; diagnostic method; Immune System; Sweden; leishmaniasis; Leishmania; immune system; chitinase; CAZy; Immune evasion; Antimicrobial peptide AMP ; Chemokine; epidemiology; Sweden; Serological assays; diagnostic method;

    Sammanfattning : This doctoral thesis consists of four separate papers, in which we; investigate epidemiological and clinical aspects of leishmaniasis in Sweden in order to increase awareness of the disease, elucidate some aspects of the interaction of the parasite and the human immune system and validate serological tools as a complement for diagnosis of leishmaniasis.. LÄS MER

  3. 3. On the Immune Regulation of Bone Response to Biomaterials

    Detta är en avhandling från Göteborgs universitet

    Författare :Ricardo Trindade; Göteborgs universitet.; Gothenburg University.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomaterial; Immune System; Osseointegration; Foreign body reaction; Immune modulation; Titanium; Copper; Polyether ether ketone; PEEK;

    Sammanfattning : Osseointegration is the biological basis for bone anchorage of oral implants, and revolu-tionized the replacement of lost teeth. It is also applied in bone anchored hearing aids and limb replacement in amputees. LÄS MER

  4. 4. The role and mechanism of ubiquitin system in innate immune regulation

    Detta är en avhandling från Umeå : Umeå University

    Författare :Swarupa Panda; Nelson O. Gekara; Fredrik Elgh; Anna Överby; Geert van Loo; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; The ubiquitin system; Deubiquitinase; MYSM1; Innate immune regulation Toll-like receptor; RIG-l like receptors; Cytoplasmic DNA receptors; NOD-like receptors; Francisella tularensis; Immune subversion; molekylärbiologi; Molecular Biology;

    Sammanfattning : Pattern-recognition receptors (PRRs) include the cell surface or endosomal membrane localized Toll-like receptors (TLRs) and the cytoplasmic PRRs such as RIG-I-like receptors (RLRs), NOD-like receptors (NLRs) and cytoplasmic DNA receptors (CDRs). Triggering of PRRs culminates in the transcriptional induction of pro-inflammatory cytokines and type I interferons (IFNs) that coordinate protection against pathogens but require tight control to avert inflammatory diseases. LÄS MER

  5. 5. The type I-E CRISPR-Cas system Biology and applications of an adaptive immune system in bacteria

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Lina Amlinger; Magnus Lundgren; Peter Fineran; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CRISPR; CRISPR-Cas; virus defense; bacteria; bacteriophage; adaptation; spacer integration; interference; gene silencing; fluorescent reporter; Escherichia coli; Mikrobiologi; Microbiology;

    Sammanfattning : CRISPR-Cas systems are adaptive immune systems in bacteria and archaea, consisting of a clustered regularly interspaced short palindromic repeats (CRISPR) array and CRISPR associated (Cas) proteins. In this work, the type I-E CRISPR-Cas system of Escherichia coli was studied.CRISPR-Cas immunity is divided into three stages. LÄS MER