Sökning: "Plasma cells"

Visar resultat 1 - 5 av 1074 avhandlingar innehållade orden Plasma cells.

  1. 1. Cholesterol in T cells : homeostasis, plasma membrane organization and signaling

    Författare :Saleemulla Mahammad; Ingela Parmryd; Thomas Harder; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plasma membrane; T cells; Cholesterol; Lipid rafts; Membrane organization; Cholesterol homeostasis; cholesteryl esters; Cell biology; Cellbiologi; Cell Biology; cellbiologi;

    Sammanfattning : The plasma membrane of eukaryotic cells contains cholesterol and glycosphingolipids enriched nanodomains known as lipid rafts; which are believed to exist in a liquid ordered (lo) state. Methyl-beta-cyclodextrin (MBCD) is used to deplete cellular cholesterol and a widespread assumption is that MBCD preferentially targets cholesterol in lipid rafts. LÄS MER

  3. 2. Peripheral immunity in patients with autoimmune endocrine diseases and the influence of physiological adaptions during pregnancy

    Författare :Louise Magnusson; Per-Ola Carlsson; Rosaura Casas; Ola Winqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Hashimoto´s thyroiditis; Graves´ disease; autoimmune Addison´s disease; antigen-presenting cells; B cells; non-classical monocytes; NK cells; memory CD8 T cells; CDCP1; SLAMF1; inflammation; lymphocyte activation; pregnancy; β-cell function; C-peptide; plasma proteome; prolactin; prokineticin-1; glucagon; oral glucose tolerance test; mass cytometry; proximity extension assay; Medicinsk vetenskap; Medical Science; Klinisk immunologi; Clinical Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), Graves’ disease (GD), and autoimmune Addison’s disease (AD) appear to share immunogenetic mechanisms. This idea is not novel, as “autoimmune tautology” is an established concept. LÄS MER

  4. 3. Modelling of Solid Oxide Fuel Cells Applied to the Analysis of Integrated Systems with Gas Turbines

    Författare :Azra Selimovic; Kraftverksteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; statistical physics; plasma; plasmas; Gaser; fluiddynamik; Termisk teknik; termodynamik; Gases; fluid dynamics; applied thermodynamics; Thermal engineering; Hybrid Cycles; Gas Turbines; Mathematical Modelling; Electrochemistry; Fuel Cells; Solid Oxide Fuel Cells; thermodynamics; Matematisk och allmän teoretisk fysik; klassisk mekanik; kvantmekanik; relativitet; gravitation; statistisk fysik; Mathematical and general theoretical physics; classical mechanics; quantum mechanics; relativity;

    Sammanfattning : Solid oxide fuel cells (SOFCs), working at high temperatures with an incomplete fuel oxidation process, have become an interesting candidate for combination with conventional power generation technology, such as gas turbines, in order to develop power plants that are both functional and efficient. An absolute condition for successful analysis and optimisation of such plants is the existence of reliable simulation tools. LÄS MER

  5. 4. Airway epithelial shedding: Morphological and functional aspects in vivo

    Författare :Jonas Erjefält; Luftvägsinflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; eosinophils; neutrophils; plasma exudation; barrier restitution; basal cells; ciliated cells; secretory cells; Epithelial repair; epithelial shedding; fibrinogen; fibronectin; Respiratory system; Andningsorganen;

    Sammanfattning : Epithelial damage may contribute to the pathology in airway diseases such as asthma and rhinitis. However, the distribution of epithelial shedding in inflammatory airway diseases and, particularly, the ensuing repair processes are largely unknown. LÄS MER

  7. 5. Studies of Cellular Regulatory Mechanisms : from Genetic Switches to Cell Migration

    Författare :Maria Werner; Erik Aurell; Ulrich Gerland; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plasma physics; Plasmafysik;

    Sammanfattning : Cellular behaviour depends ultimately on the transcription of genes. If we know how transcription is controlled we have a better chance of understanding cellular processes. This thesis presents six studies, all concerning cellular regulatory mechanisms. One study is purely experimental and five are computational studies. LÄS MER