Sökning: "DZNep"

Hittade 2 avhandlingar innehållade ordet DZNep.

1. 1. A long and winding road: Differentiating human embryonic stem cells into dopaminergic neurons

   Författare :Oktar Guloglu; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocyte; PA6; DZNEP; dopaminergic differentiation; embryonic stem cells;

   Sammanfattning : Parkinson’s disease is a progressive neurodegenerative disorder. Since the motor manifestations of the disease is associated with the loss of dopaminergic (DAergic) neurons in the substantia nigra pars compacta, cell replacement therapy is a promising approach for treatment. LÄS MER

3. 2. Tumour Survival Signals and Epigenetic Gene Silencing in Multiple Myeloma : Implications for Biology and Therapy

   Författare :Charlotte Fristedt Duvefelt; Helena Jernberg-Wiklund; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple myeloma; Polycomb; apoptosis; cIAP2; IAP-inbibitors; proteasome inhibitors; LBH589; PPP; DZNep;

   Sammanfattning : This thesis is focused on multiple myeloma (MM), a haematological malignancy that still remains incurable. The pathogenesis of MM is not fully understood and there is a large intra-tumour and interclonal genetic variation in MM patients. LÄS MER