Sökning: "erythrocyte rosetting"

Visar resultat 6 - 10 av 15 avhandlingar innehållade orden erythrocyte rosetting.

1. 6. Periodontal disease in adolescents with Down syndrome

   Författare :Monica Barr Agholme; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Plasmodium falciparum; malaria; erythrocyte rosetting; humoral immunity; glycosaminoglycan; heparan sulfate; heparin; ABO blood groups; Plasmodium falciparum erythrocyte membrane protein 1; var genes;

   Sammanfattning : Characterization of virulence factors in P. falciparum malaria is essential in order to identify new therapeutic and prophylactic targets. Rosette formation, the binding of uninfected red blood cells to parasite-infected red blood cells, is a P. falciparum virulence phenotype associated with severe clinical manifestations, e. LÄS MER

3. 7. Carbohydrate-mediated adhesion in Plasmodium falciparum malaria

   Författare :Antonio Barragan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Plasmodium falciparum; malaria; erythrocyte rosetting; humoral immunity; glycosaminoglycan; heparan sulfate; heparin; ABO blood groups; Plasmodium falciparum erythrocyte membrane protein 1; var genes;

   Sammanfattning : Characterization of virulence factors in P. falciparum malaria is essential in order to identify new therapeutic and prophylactic targets. Rosette formation, the binding of uninfected red blood cells to parasite-infected red blood cells, is a P. falciparum virulence phenotype associated with severe clinical manifestations, e. LÄS MER

4. 8. Heparan sulfate dependent sequestration during Plasmodium falciparum malaria

   Författare :Anna Vogt; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Severe malaria; Plasmodium falciparum; sequestration; endothelial adhesion; erythrocyte rosetting; PfEMP1; DBL1alpha; heparan sulfate; heparin; animal model.;

   Sammanfattning : Plasmodium falciparum infected erythrocytes are able to bind to the microvascular endothelium (cytoadherence), and to uninfected erythrocytes (rosetting) that lead to excessive sequestration of the parasites. This causes obstruction of the deep microvasculature by P. LÄS MER

5. 9. Sequestration, virulence, and future interventions in Plasmodium falciparum malaria

   Författare :Fredrik Pettersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Severe malaria; Plasmodium falciparum; sequestration; endothelial adhesion; erythrocyte rosetting; PfEMP1; DBL1alpha; animal model; vaccine; adjuvant treatment;

   Sammanfattning : The Plasmodium falciparum infected erythrocyte (iRBC) withdraws from the peripheral circulation to hide in the deep microvasculature during maturation. This phenomena, referred to as sequestration, is believed to cause extensive clogging of the vessels and contribute to die development of severe malaria. LÄS MER

7. 10. Immunoglobulins in the adhesion of Plasmodium falciparum-infected erythrocytes in malaria

   Författare :Carin Scholander; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Plasmodium falciparum; rosetting; cytoodhesion; immunoglobulins; serum proteins; fibrillar structures; malarial anaemia; placental malaria; PfEMP1;

   Sammanfattning : Characterisation of the delicate cell-to-cell interactions involved in the binding of Plasmodium falciparum- infected erythrocytes to host cells is central for the understanding of the development of severe malaria. Infected erythrocytes adhere in the deep vasculature of several organs, sequestration, leading to cerebral malaria, pulmonary oedema or renal failure. LÄS MER