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Visar resultat 1 - 5 av 15 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Antigenic variation in relapsing fever Borrelia

    Författare :Nils Burman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; Relapsing fever; Antigenic variation; Vmp lipoprotein; Rosetting;

    Sammanfattning : The spirochete Borrelia hermsii avoids the immune response of its mammalian host through multiphasic antigenic variation. Serotype specificity is determined by Variable major proteins (Vmp), in the outer membrane. LÄS MER

  3. 2. Endothelial cytoadherence, rosetting and virulence in Plasmodium falciparum malaria

    Författare :Andreas Heddini; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum; malaria; endothelial adhesion; erythrocyte rosetting; PECAM- 1 CID3 1; immunoglobulins; cerebral malaria; PfEMP- 1; var-genes;

    Sammanfattning : Excessive sequestration of Plasmodium falciparum-infected erythrocytes (pRBC) and uninfected erythrocytes directly blocks the microcirculation and precipitates severe symptoms from the affected organ and is thereby thought to be responsible for the severe complications which may occur during P. falciparum infection. LÄS MER

  4. 3. Virulence in Plasmodium falciparum malaria : mechanisms of PfEMP1-mediated rosetting

    Författare :Davide Angeletti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is one of the most important infectious diseases in the world and the Plasmodium falciparum parasite is the causative agent of most of the severe cases. The pathogenesis of the disease is complex but sequestration and hence microvascular obstruction is associated with virulence of the parasite. LÄS MER

  5. 4. Malaria and polypeptides of Plasmodium falciparum at the infected erythrocyte surface

    Författare :Mia Palmkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is one of the top three most lethal infectious diseases in the world after tuberculosis and HIV. The disease is caused by intracellular parasites of the genus Plasmodium spp. LÄS MER

  7. 5. Host cell adhesion of Plasmodium falciparum-infected erythrocytes

    Författare :Carl Johan Treutiger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum; erythrocyte rosetting; cytoadherence; cerebral malaria; PfEMPI; serum proteins; PECAM-I CD31;

    Sammanfattning : Excessive binding of Plasmodium falciparum-infected erythrocytes to the microvascular endothelium (cytoadherence) and to uninfected eryrthrocytes (rosetting) are regarded as key-events in the development of a severe malaria infection. P. falciparum rosetting was confirmed to be associated with the development of cerebral malaria in The Gambia. LÄS MER