Sökning: "adjuvant treatment"

Visar resultat 1 - 5 av 216 avhandlingar innehållade orden adjuvant treatment.

  1. 1. Cell cycle alterations and 11q13 amplification in breast cancer : prediction of adjuvant treatment response

    Författare :Marie Ahnström Waltersson; Olle Stål; Marie-Louise Fjällskog; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The growth and development of the breast is to a large extent regulated by oestrogens through the oestrogen receptor (ER). Activation of the ERα triggers transcription of genes that are important for cell proliferation and stimulates entry into the G1 phase of the cell cycle. LÄS MER

  2. 2. Long-term effects of adjuvant tamoxifen treatment on cardiovascular disease and cancer

    Författare :Johan Rosell; John Carstensen; Olle Stål; Bo Nordenskjöld; Lars Holmberg; Linköpings universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adjuvant; adverse events; breast cancer; cerebrovascular disease; coronary heart disease; heart failure; lung cancer; second primary cancer; tamoxifen;

    Sammanfattning : The aims of this thesis were to investigate the long-term effects of adjuvant tamoxifen treatment on breast cancer recurrence and mortality, cardiovascular disease, and the incidence of secondary cancer.Between 1982 and 1992, postmenopausal patients with early stage breast cancer were included in a randomized clinical study of 2 or 5 years of postoperative tamoxifen therapy. LÄS MER

  3. 3. Bacterial Vaginosis : Diagnosis, Prevalence, and Treatment

    Författare :Katarina Eriksson; Per-Göran Larsson; Urban Forsum; Ann-Sofie Adolfsson; Inger Mattsby-Baltzer; Linköpings universitet; []
    Nyckelord :Bacterial vaginosis; prevalence; diagnosis; PAP-smear; probiotic treatment; clindamycin; MEDICINE; MEDICIN;

    Sammanfattning : Bacterial Vaginosis (BV) is a disorder of unknown etiology, characterized by a foul smelling vaginal discharge, loss or reduction of the normal vaginal Lactobacilli, and overgrowth of other anaerobic bacteria. Thus, it presents a formidable problem for clinicians as well as microbiologists researching its etiology, clinical course, treatment, and epidemiology. LÄS MER

  4. 4. Gastrointestinal stromal tumours. On diagnosis and treatment

    Författare :Per Bümming; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :adjuvant; epidemiology; GIST; imatinib; KIT; mutation; neoadjuvant; neuroendocrine phenotype; PET; prognosis; surgery; vesicle proteins;

    Sammanfattning : Gastrointestinal stromal tumours (GIST) are thought to originate from the interstitial cells of Cajal, which show many properties in common with neurons of the gastrointestinal tract. High-risk GIST has a very poor prognosis and tumour recurrence is common after intentionally curative surgery. LÄS MER

  5. 5. Folates in the treatment of colorectal cancer

    Författare :Helena Taflin; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Folate; Colorectal cancer; leucovorin; modufolin; LC-MS MS; polymorphisms; MTHFR; adjuvant chemotherapy;

    Sammanfattning : ABSTRACT Folates in the Treatment of Colorectal Cancer Department of Surgery Institute of Clinical Sciences at Sahlgrenska Academy University of Gothenburg Helena Taflin Background: Colorectal cancer is one of the most common cancers in the world, and radical surgery with total removal of the tumour (RO-resection) is the single most important treatment. However, chemotherapy is recommended for patients with risk factors and patients with metastatic disease. LÄS MER