Sökning: "differential coding"

Visar resultat 16 - 20 av 46 avhandlingar innehållade orden differential coding.

  1. 16. Exploring Brain Gene Expression i Animal Models of Behaviour

    Författare :Julia Lindberg; Elena Jazin; Peter Saetre; Jonathan Flint; Uppsala universitet; []
    Nyckelord :Biology; behavioural genetics; gene expression; brain; microarray analysis; domestication; animal model; haem; Canis familiaris; Vulpes vulpes; Mus musculus; Biologi;

    Sammanfattning : The genetic basis for behavioural traits is largely unknown. The overall aim of this thesis was to find genes with importance for behavioural traits related to fear and anxiety. Microarray analysis was used to screen expression profiles of brain regions important for emotional behaviour in dogs, wolves, foxes and mice. LÄS MER

  3. 17. Targeted proteomics methods for protein quantification of human cells, tissues and blood

    Författare :Fredrik Edfors; Mathias Uhlén; Albert Heck; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteomics; mass spectrometry; protein quantification; stable isotope standard; parallel reaction monitoring; immuno-enrichment; Bioteknologi; Biotechnology;

    Sammanfattning : The common concept in this thesis was to adapt and develop quantitative mass spectrometric assays focusing on reagents originating from the Human Protein Atlas project to quantify proteins in human cell lines, tissues and blood. The work is based around stable isotope labeled protein fragment standards that each represent a small part of a human protein-coding gene. LÄS MER

  4. 18. The genetic mechanism that links Hutchinson-Gilford progeria syndrome to physiological aging

    Författare :Sofía Rodríguez Vásquez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Aging is a complex process that is not completely understood. The study of segmental progeroid syndromes such as Hutchinson-Gilford progeria syndrome (HGPS) has allowed us to connect the common genetic mechanisms that occur in normal physiological aging, with the cellular alterations presented by this severe premature aging syndrome. LÄS MER

  5. 19. Accounting standard-setting through adaptation: Models and Contextual Factors in the Case of the Swedish Standard K3

    Författare :Tina Sigonius; Handelshögskolan i Stockholm; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : Back cover text: As an alternative to drafting standards from scratch, many accounting standard-setters make use of existing standards. Thereby, they adopt an existing standard or use an existing standard as a model subject to adaptation. In national accounting standard-setting, adoption typically proves neither desirable nor possible. LÄS MER

  7. 20. Functional epigenetic analyses in the context of psychiatric health in adolescence

    Författare :Diana-Maria Manu; Helgi B. Schiöth; Elena Raffetti; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Adolescence is a unique and formative period for learning and developing skills and abilities for adulthood. The prevalence of mental health problems in adolescents is estimated to 10-20%, being a major risk for suicide, social and academic impairments. Suicide is the third leading cause of death in older adolescents (15-19 years). LÄS MER