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Hittade 3 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Fine needle aspiration diagnosis of spindle cell tumors of soft tissue, including the use of ancillary methods, and correlation with clinical data

    Författare :Henryk Domanski; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patologi allmän ; patologisk anatomi; General pathology; pathological anatomy; spindle cell lipoma; soft tissue; spindle cell tumors; Medicine human and vertebrates ; Medicin människa och djur ; schwannoma; neurilemoma; leiomyosarcoma; immunocytochemistry; FNA; fine needle aspiration; dermatofibrosarcoma protuberans; elastofibroma dorsi; Cytology; electron microscopy;

    Sammanfattning : Fine needle aspiration cytology (FNAC) is gaining increased popularity in the diagnosis of soft tissue lesions. FNAC used as a primary examination method to obtain a morphologic diagnosis, has been part of the diagnostic work-up of patients admitted to the Musculoskeletal Tumor Center of the Lund University Hospital since 1972. LÄS MER

  3. 2. The role of PDGFB in dermatofibrosarcoma protuberans and giant cell fibroblastoma

    Författare :Kevin P O'Brien; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dermatofibrosarcoma protuberans; giant cell fibroblastoma; translocation; FISH; translocation breakpoint; fusion gene; oncogene; Platelet derived growth factor B-chain; collagen type I alpha 1; tumor formation; autocrine stimulation;

    Sammanfattning : Dermatofibrosarcoma protuberans (DFSP) and giant cell fibroblastoma (GCF) are rare invasive tumors of the dermis. GCF is considered the juvenile form of DFSP. Both DFSP and GCF are characterized by the presence of chromosomal aberrations involving chromosomes 17 and 22. LÄS MER

  4. 3. Paracrine and autocrine functions of PDGF in malignant disease

    Författare :Tobias Sjöblom; Lars Holmgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Cellbiologi; Cell biology; Cellbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : Growth factors and their receptors are frequently activated by mutations in human cancer. Platelet-derived growth factor (PDGF)-B and its tyrosine kinase receptor, the PDGF β-receptor, have been implicated in autocrine transformation as well as paracrine stimulation of tumor growth. LÄS MER