Sökning: "cytokine"
Visar resultat 26 - 30 av 1092 avhandlingar innehållade ordet cytokine.
26. CXCL16 and CD137 in atherosclerosis
Sammanfattning : Atherosclerosis is a progressive inflammatory disease that is characterized by the accumulation of lipids, infiltrated cells and fibrous elements in large arteries. This thesis focuses on the molecular mechanisms behind foam cell formation and inflammation, two central processes in the development of atherosclerosis. LÄS MER
27. Clinical, epidemiological and immunological aspects of Lyme borreliosis with special focus on the role of the complement system
Sammanfattning : Lyme borreliosis (LB) is the most common vector-borne disease in the Northern Hemisphere. The infection is caused by spirochetes belonging to the Borrelia burgdorferi sensu lato complex, and it is transmitted to humans by ticks. LÄS MER
28. Allergic airway inflammation and bone marrow eosinophilopoiesis. Modulation by cytokines
Sammanfattning : Accumulation of eosinophils in the airways and lung parenchyma is one of the hallmarks of allergic airway inflammation. This cellular inflammatory response is likely to involve the release of eosinophils from peripheral storage pools and possibly cause production of eosinophils in the bone marrow (BM). LÄS MER
29. Role of Inducible Nitric Oxide Synthase and Melatonin in Regulation of β-cell Sensitivity to Cytokines
Sammanfattning : The mechanisms of β-cell destruction leading to type 1 diabetes are complex and not yet fully understood, but infiltration of the islets of Langerhans by autoreactive immune cells is believed to be important. Activated macrophages and T-cells may then secrete cytokines and free radicals, which could selectively damage the β-cells. LÄS MER
30. In vitro Studies of β-cell Death and Survival. Modulation by Adenoviral Vectors and Bcl-2 Overexpression
Sammanfattning : Type 1 diabetes is a multifactorial disease resulting from the selective destruction of insulin-producing β-cells within the pancreatic islets of Langerhans. The mechanisms of β-cell death are not fully understood but cytokines are important mediators of this process. LÄS MER