Sökning: "childhood leukemia"

Visar resultat 21 - 25 av 52 avhandlingar innehållade orden childhood leukemia.

  1. 21. Register-based studies on childhood cancer : relapsed childhood acute lymphoblastic leukemia and skeletal adverse events in childhood cancer survivors in the Nordic countries

    Författare :Trausti Óskarsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Although cancer is a rare disease in children, it is the leading disease-related cause of death in children and adolescents in developed countries. Currently 80% of patients become long-time survivors but if a relapse occurs the outcome for most patients is still poor. LÄS MER

  3. 22. DNA methylation as a prognostic marker i acute lymphoblastic leukemia

    Författare :Magnus Borssén; Sofie Degerman; Kim Vettenranta; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA methylation; acute lymphoblastic leukemia; T-ALL; Relapse; Telomere length; patologi; Pathology; Pediatrics; pediatrik;

    Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Most ALL cases originate from immature B-cells (BCP-ALL) and are characterized by reoccurring structural genetic aberrations. These aberrations hold information of the pathogenesis of ALL and are used for risk stratification in treatment. LÄS MER

  4. 23. Genetic studies of acute lymphoblastic leukemia

    Författare :Ekaterina Kuchinskaya; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy, comprising approximately 25% of all childhood cancers. A huge improvement in outcome of children with ALL during the last 20 years has resulted in remission rates exceeding 95% and a 5 year event-free-survival approaching 80%. LÄS MER

  5. 24. Identification and evaluation of novel prognostic genetic markers for childhood acute lymphoblastic leukemia

    Författare :Ingegerd Ivanov Öfverholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Childhood acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer today. Due to advances in risk stratification and treatment, survival rates have increased drastically the last decades. Currently, children with acute leukemia in the Nordic countries are diagnosed and treated according to the NOPHO-2008 treatment protocol. LÄS MER

  7. 25. Childhood malignant disease and consequences for growth hormone secretion, intellectual function and cardiovascular risk

    Författare :Katarina Link; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone deficiency; Insulin sensitivity; Cranial radiotherapy; Neuropsychological performance; Endocrinology; secreting systems; diabetology; Acute Lymphoblastic leukemia; diabetologi; sekretion; Endokrinologi;

    Sammanfattning : In childhood onset growth hormone deficiency (GHD) a reduction in cardiac left ventricular mass (LVMi) and impairment of cardiac systolic function, as well as in glomerular filtration rate (GFR) has been shown. In study I, we showed that a low dose of GH treatment for 10 months resulted in increased LVMi and kidney size. LÄS MER