Sökning: "childhood leukemia"

Visar resultat 16 - 20 av 52 avhandlingar innehållade orden childhood leukemia.

  1. 16. Molecular studies of prognostic and etiological factors in childhood leukemia

    Författare :Vasilios Zachariadis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common cancer in childhood. It is caused by the somatic acquisition of genetic abnormalities and malignant transformation of immature lymphocytes in the bone marrow, most commonly of B-cell lineage. LÄS MER

  3. 17. WILMS’ TUMOUR GENE 1 PROTEIN (WT1) – AN EFFECTOR IN LEUKEMOGENESIS?

    Författare :Karina Vidovic; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; WT1 delZ ; leukemia; BCR ABL1; hematopoiesis; NDRG2; IRF8; WT1;

    Sammanfattning : Wilms’ tumour gene 1 (WT1) encodes a zinc-finger transcription factor functioning as a key regulator in organ development. WT1 was first identified as a tumour suppressor gene due to its inactivation in Wilms’ tumour cases, a childhood kidney cancer. LÄS MER

  4. 18. Cardiopulmonary Function in Healthy Individuals and in Patients After Hematopoietic Cell Transplantation

    Författare :Margareta Genberg; Andrei Malinovschi; Eva Nylander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hematopoietic stem cell transplantation; echocardiography; cardiopulmonary execise testing; stress testing; onchology; childhood leukemia; healthy adults; breathing reserve; oxygen uptake; Clinical Physiology; Klinisk fysiologi;

    Sammanfattning : Background: The cardiopulmonary exercise test (CPET) is the gold standard of clinical exercise tests, combining conventional stress testing with measurement of oxygen uptake and carbon dioxide production. In order to interpret CPET findings, adequate reference values are needed. Currently, no Swedish reference values exist. LÄS MER

  5. 19. Unwinding the layers of high hyperdiploid childhood acute lymphoblastic leukemia

    Författare :Larissa Helena Moura-Castro; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; acute lymphoblastic leukaemia ALL ; high hyperdiploid ALL; chromatin structure; transcriptional regulation; CTCF; cohesin; clonal heterogeneity;

    Sammanfattning : .... LÄS MER

  7. 20. Immune reconstitution after childhood leukemia. Aspects on immunizations and effects of Ara-C on the innate immune system

    Författare :Torben Ek; Göteborgs universitet; []
    Nyckelord :acute lymphoblastic leukemia; immune reconstitution; immunization; antibody; avidity; ara-C; fever; cytokines;

    Sammanfattning : Children with acute lymphoblastic leukemia (ALL) can be cured with cytotoxic chemotherapy, but myelosuppression and immunosuppression are major side effects causing morbidity and even mortality from infections. Vaccinations with diphtheria toxoid (DT), tetanus toxoid (TT) and protein conjugated Haemophilus influenzae type B (Hib) capsular polysaccharide were used to investigate the adaptive immune system in a controlled study of 31 children after treatment for ALL. LÄS MER