Sökning: "cerebrospinal fluid"

Visar resultat 6 - 10 av 452 avhandlingar innehållade orden cerebrospinal fluid.

  1. 6. Fluid dynamic principles for analysis of intracranial pressure control : application towards space medicine and hydrocephalus

    Författare :Petter Holmlund; Anders Eklund; Sara Qvarlander; Jan Malm; Marek Czosnyka; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intracranial pressure; posture; cerebrospinal fluid; microgravity; venous collapse; internal jugular vein; fluid dynamics; venous pressure; spaceflight-associated neuro-ocular syndrome; hydrocephalus; mathematical modeling; ultrasound; magnetic resonance imaging;

    Sammanfattning : Intracranial pressure (ICP) is an important component of the fluid dynamic environment of the brain and plays a central role with regards to the maintenance of normal cerebral blood flow and neuronal function. However, many regulatory mechanisms controlling the ICP are still poorly understood. LÄS MER

  3. 7. Zinc in cerebrospinal fluid and serum in some neurological diseases

    Författare :Ragnar Palm; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; zinc; copper; serum; cerebrospinal fluid; albumin; multiple sclerosis; epilepsy; phenytoin; blood brain barrier damage; subarachnoid haemorrhage.;

    Sammanfattning : The trace elements zinc and copper are essential components of many enzymes, some of which are of importance for the development and function of the central nervous system. Deficiency of the metals has been shown to lead to malformations and to the loss of myelin in animals. LÄS MER

  4. 8. Proteomic strategies for analysis of cerebrospinal fluid in neurodegenerative disorders

    Författare :Sara Folkesson Hansson; Göteborgs universitet; []
    Nyckelord :Alzheimer?s disease; frontotemporal dementia; cerebrospinal fluid; neurodegeneration; proteomics; mass spectrometry; prefractionation; protein identification; quantification;

    Sammanfattning : ABSTRACT There is a great need for biomarkers to diagnose neurodegenerative disorders, such as the cognitive disorders Alzheimer?s disease (AD) and frontotemporal dementia (FTD). Cerebrospinal fluid (CSF) is in contact with the extracellular fluid of the brain and is consequently a valuable medium for identifying biomarkers for neurological disorders. LÄS MER

  5. 9. Cerebrospinal fluid biomarkers for differentiating between Alzheimer’s disease and Vascular dementia

    Författare :Maria Bjerke; Göteborgs universitet; []
    Nyckelord :Vascular dementia; Alzheimer s disease; biomarkers; cerebrospinal fluid;

    Sammanfattning : Patients suffering from mild cognitive impairment (MCI) run a higher risk of developing dementia, with Alzheimer’s disease (AD) being the most common form. Vascular dementia (VaD) is proposed to be the second most common dementia entity, and it includes the clinically relatively homogenous subgroup of subcortical vascular dementia (SVD). LÄS MER

  7. 10. Cerebrospinal fluid peptidomics: discovery of endogenous peptides as biomarkers of Alzheimer's disease

    Författare :Karl Hansson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Biomarkers; Mass spectrometry; Cerebrospinal fluid; Liquid Chromatography; Endogenous peptides;

    Sammanfattning : Neurodegenerative diseases (NDs), the most prominent example of which is Alzheimer’s disease (AD), has turned out to be among the greatest challenges for modern medicine. Common characteristics of NDs involve the aggregation of proteins, progressive loss of neuronal cells in specific regions of the central nervous system (CNS) and as a result – cognitive and/or functional decline. LÄS MER