Sökning: "cell loss"
Visar resultat 16 - 20 av 1247 avhandlingar innehållade orden cell loss.
16. Biological consequences of endothelial cell signaling
Sammanfattning : Endothelial cells make up the inner lining of blood and lymphatic vessels, where they participate in functions vital to survival of the tissue; endothelial cells maintain vessel integrity, dynamically respond to the changing metabolic needs of tissues, and participate in many tissue-specific functions. Endothelial cells sense environmental cues which initiate signal transduction pathways that regulate behavior. LÄS MER
17. DNA methylation in T cell leukaemia
Sammanfattning : T cell acute lymphoblastic leukaemia (T-ALL) is a predominantly paediatric cancer that stems from malignant transformation of developing T cells. While the disease has an overall survival rate of 80%, the intense chemotherapy treatment causes severe toxicity and long-term side effects. LÄS MER
18. Studies of individual pancreatic -cells : Electrophysiological analysis of rhythmic behaviour and development of new techniques
Sammanfattning : The insulin concentration in blood varies periodically, which is believed to prevent down-regulation of the hormone receptors. Loss of the regular insulin oscillations is considered to be an early sign of developing diabetes. LÄS MER
19. Islet insulin secretory patterns in diabetes and the role of UCP2
Sammanfattning : During development of type 1 and type 2 diabetes plasma insulin patterns are altered. Since the islet insulin release pattern has been implicated in this development, insulin secretion from single islets was studied and linked to the islet protein levels of uncoupling protein-2 (UCP2). LÄS MER
20. Challenges in Islet Transplantation and Strategies to Improve Beta-Cell Function
Sammanfattning : The incidence of type 1 diabetes is increasing worldwide and therapies of islet transplantation and potential cell-based therapies are rapidly evolving. Choosing the optimal site for such therapies is crucial for safety and for obtaining the best possible outcome. LÄS MER