Sökning: "carbamazepine"

Visar resultat 6 - 10 av 36 avhandlingar innehållade ordet carbamazepine.

  1. 6. Central pain in multiple sclerosis : clinical characteristics, sensory abnormalities and treatment

    Författare :Anders Österberg; Per Hansson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : In the present research programme the occurrence of pain in MS was investigated, with special emphasis on central pain (CP). Questionnaires were sent to all 429 patients with definite MS in the patient register at our neurology department. LÄS MER

  3. 7. Studies on 4b-hydroxycholesterol, a marker of CYP3A activity, and its association with 25-hydroxyvitamin D

    Författare :Hanna Nylén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cholesterol is a vital compound that can undergo cytochrome P450 (CYP) mediated conversion into steroid hormones, bile acids and oxysterols. CYP enzymes are present in all human tissues and mediate the metabolism of several endogenous and exogenous compounds such as steroids and drugs. LÄS MER

  4. 8. Pharmaceutical compounds; a new challenge for wastewater treatment plants

    Författare :Maja Dlugolecka; Elzbieta Plaza; Bengt Hultman; Nicklas Paxéus; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; activated sludge; biodegradation; granular activated carbon GAC ; membrane bioreactor MBR ; pharmaceutical compounds; wastewater; Water engineering; Vattenteknik;

    Sammanfattning : Analytical analyses conducted at the Himmerfjärden WWTP (285.000 PE connected) identified 70 pharmaceutical compounds belonging to different therapeutic classes. Such organic micropollutants at low detected concentration range of µg - ng l-1 did not affect the treatment processes at WWTP. LÄS MER

  5. 9. Pharmacodynamics of Enzyme Induction and its Consequences for Substrate Elimination

    Författare :Mats O. Magnusson; Rikard Sandström; Mats Karlsson; Ulf Bredberg; Uppsala universitet; []
    Nyckelord :Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Pharmacodynamics; Enzyme induction; Time course; Turnover model; Mechanism-based; Modelling; NONMEM; Farmakokinetik Farmakoterapi;

    Sammanfattning : Enzyme induction is a process whereby a molecule enhances the expression of enzymes. If the affected enzymes are involved in the elimination of a drug, this may result in a drug interaction. Induction is therefore of major concern during drug development and in clinical practice. LÄS MER

  7. 10. Ozonation as sewage effluent treatment : toxicological effects in adult and embryonic zebrafish, Danio rerio

    Författare :Johannes Pohl; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Pharmaceutical residues are not efficiently removed by current sewage treatment plant (STP) technologies. This allows for the release of pharmaceutical residues into the aquatic environment. Pharmaceuticals and their metabolites are problematic because they are designed to affect biological processes in non-target aquatic species. LÄS MER