Sökning: "biobank research"

Visar resultat 6 - 10 av 50 avhandlingar innehållade orden biobank research.

  1. 6. Depression : genetic, epigenetic and DNA biobank studies

    Författare :Philippe A Melas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Depression is a disease that has an estimated lifetime prevalence of ~15% and a heritability of ~36%. There is support for a heterogeneous etiology of depression, which includes: a) numerous genetic loci, b) various epigenetic contributors, and c) different environmental risk factors. LÄS MER

  3. 7. Establishment and applications of a multiple sclerosis biobank : analysis of biomarkers and therapeutic complications in MS

    Författare :Ellen Iacobaeus; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Biomarkers for disease activity and prognosis in multiple sclerosis (MS) are lacking. We established a MS biobank consisting of paired cerebrospinal fluid samples (CSF) and peripheral blood samples from MS patients and controls. LÄS MER

  4. 8. Environmental Toxins and Essential Trace Elements at Delivery and ADHD

    Författare :Amanda Ode; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PFCs; manganese; selenium; phthalates; ADHD; fetus;

    Sammanfattning : Perfluorinated compounds (PFCs), phthalates, manganese and selenium are ubiquitous in the environment and humans and influence fetal growth and development. Register and biobank based case-control studies were conducted to investigate the relationship between prenatal exposure to these chemicals and attention deficit hyperactivity disorder (ADHD) in childhood. LÄS MER

  5. 9. Maternal smoking during pregnancy - Long-term health effects in the offspring

    Författare :Kristina Mattsson; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Maternal smoking during pregnancy; Medical Birth Register; long-term health effects; register validation; biomarker;

    Sammanfattning : Globally, around 10 % of women smoke during pregnancy today. It is known that pregnancy smoking increases the risk of adverse short-term health effects in the offspring, such as preterm birth, low birthweight and spontaneous abortion. Less is known about whether any adverse health effects persist until adulthood. LÄS MER

  7. 10. Triggers of autoimmunity. Studies on gestational events

    Författare :Sabina Lindehammer; Celiaki och diabetes; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet autoantibodies; pregnancy; type 1 diabetes; celiac disease;

    Sammanfattning : Objective The primary aim of this thesis was to test whether gestational exposure to environmental factors may induce islet autoimmunity. The second aim was to determine to what extent the exposure to viruses or other environmental factors is a risk factor for type 1 diabetes in the offspring. LÄS MER