Sökning: "binding specificities"

Visar resultat 26 - 30 av 62 avhandlingar innehållade orden binding specificities.

  1. 26. Applications of Chromophores and Multiphoton Techniques to Study Structure and Interactions of Bio-macromolecules in Assembled State

    Författare :Piotr Hanczyc; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Z-scan; One-photon spectroscopy; oxazole yellow dyes; two-photon absorption.; non-linear spectroscopy; PVA DNA dyes films; linear dichroism; ruthenium complexes;

    Sammanfattning : The research presented in this thesis is concerned with the linear and nonlinear optical properties of biopolymers and the chromophores that bind to them. This thesis combines analyses of the interactions of biomolecules with technological improvements of already existing systems for bionanotechnology-related research. LÄS MER

  3. 27. Identification of new proteins and biological processes in the apicomplexan Toxoplasma gondii

    Författare :Silvia Botero-Kleiven; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The apicomplexan protozoan Toxoplasma gondii is a ubiquitous parasite of humans and animals. Entering its host through the digestive system, it possesses the ability to rapidly disseminate in the body and infect a wide range of tissues and cells. LÄS MER

  4. 28. Affibody ligands in immunotechnology applications

    Författare :Jenny Rönnmark; KTH; []
    Nyckelord :phage display; combinatorial; affinity; IgA ligand; immunohistochemistry; affibody-fusions;

    Sammanfattning : This thesis describes the development and use ofnon-immunoglobulin affinity proteins denoted affibodies asalternatives to antibodies in different immunotechnologyapplications. A 58 aa IgG Fc binding three-helix bundle domainZ, derived from staphylococcal protein A has been used asframework for library constructions, in which the face of themolecule involved in the native binding activity has beenengineered by combinatorial protein engineering. LÄS MER

  5. 29. Regulation of Heparan Sulfate 6-O-Sulfation Patterns

    Författare :Anh-Tri Do; Marion Kusche-Gullberg; Ulf Lindahl; Malcolm Lyon; Uppsala universitet; []
    Nyckelord :Biochemistry; Heparan Sulfate; Biosynthesis; 6-O-sulfation; 6-O-sulfotransferases; 6-O-endosulfatases; Nematostella; Biokemi;

    Sammanfattning : Heparan sulfates (HSs) are linear, negatively charged polysaccharides composed of alternating hexuronic acid (glucuronic acid or iduronic acid) and glucosamine residues that can be substituted to varying degrees with sulfate groups. HS, localized in the extracellular matrix and on the surface of most cells, interacts with a large number of proteins. LÄS MER

  7. 30. The use of peptides for studying molecular events in HIV- and HSV-infections

    Författare :Michael Levi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Synthetic peptides were used as tools in order to study various characteristic sof human immunodeficiency virus (HIV) and herpes simplex virus (HSV). Peptides were designed as multiple antigenic peptides (MAPs) and used as HIV vaccines in experimental animals. The included HIV epitopes were more immunogenic when immunized as MAPs than as a protein. LÄS MER